Environmental paleomicrobiology: using DNA preserved in aquatic sediments to its full potential

E Capo, ME Monchamp, MJL Coolen… - Environmental …, 2022 - Wiley Online Library
In‐depth knowledge about spatial and temporal variation in microbial diversity and function
is needed for a better understanding of ecological and evolutionary responses to global …

Natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic

M Klapper, A Hübner, A Ibrahim, I Wasmuth, M Borry… - Science, 2023 - science.org
Major advances over the past decade in the field of ancient DNA are providing access to
past paleogenomic diversity, but the diverse functions and biosynthetic capabilities of this …

Exploring different methodological approaches to unlock paleobiodiversity in peat profiles using ancient DNA

I Fracasso, C Zaccone, N Oskolkov, L Da Ros… - Science of the Total …, 2024 - Elsevier
Natural and human-induced environmental changes deeply affected terrestrial ecosystems
throughout the Holocene. Paleoenvironmental reconstructions provide information about the …

Early human impact on lake cyanobacteria revealed by a Holocene record of sedimentary ancient DNA

EC Nwosu, A Brauer, ME Monchamp… - Communications …, 2023 - nature.com
Sedimentary DNA-based studies revealed the effects of human activity on lake
cyanobacteria communities over the last centuries, yet we continue to lack information over …

Metagenomic analysis of Mesolithic chewed pitch reveals poor oral health among stone age individuals

E Kırdök, N Kashuba, H Damlien, MA Manninen… - Scientific reports, 2024 - nature.com
Prehistoric chewed pitch has proven to be a useful source of ancient DNA, both from
humans and their microbiomes. Here we present the metagenomic analysis of three pieces …

Phylogeny and disease associations of a widespread and ancient intestinal bacteriophage lineage

PA de Jonge, BJH van den Born… - Nature …, 2024 - nature.com
Viruses are core components of the human microbiome, impacting health through
interactions with gut bacteria and the immune system. Most human microbiome viruses are …

Ancient metagenomic studies: considerations for the wider scientific community

C Der Sarkissian, IM Velsko, AK Fotakis, ÅJ Vågene… - Msystems, 2021 - Am Soc Microbiol
Like modern metagenomics, ancient metagenomics is a highly data-rich discipline, with the
added challenge that the DNA of interest is degraded and, depending on the sample type, in …

Sedimentary ancient DNA: a new paleogenomic tool for reconstructing the history of marine ecosystems

NL Nguyen, D Devendra, N Szymańska… - Frontiers in Marine …, 2023 - frontiersin.org
Sedimentary ancient DNA (seda DNA) offers a novel retrospective approach to
reconstructing the history of marine ecosystems over geological timescales. Until now, the …

metaDMG–a fast and accurate ancient DNA damage toolkit for metagenomic data

C Michelsen, MW Pedersen, A Fernandez-Guerra… - bioRxiv, 2022 - biorxiv.org
Motivation Under favourable conditions DNA molecules can persist for hundreds of
thousands of years. Such genetic remains make up invaluable resources to study past …

Detection of ancient viruses and long-term viral evolution

L Nishimura, N Fujito, R Sugimoto, I Inoue - Viruses, 2022 - mdpi.com
The COVID-19 outbreak has reminded us of the importance of viral evolutionary studies as
regards comprehending complex viral evolution and preventing future pandemics. A unique …