Podocalyxin, a sialomucin most closely related to CD34 and endoglycan, is expressed by
kidney podocytes, hematopoietic progenitors, vascular endothelia, and a subset of neurons; …

CD34, podocalyxin, and endoglycan are members of a family of single-pass transmembrane
proteins that show distinct expression on early hematopoietic precursors and vascular …

Epithelial polarization involves the segregation of apical and basolateral membrane
domains, which are stabilized and maintained by tight junctions and membrane traffic. We …

We have previously identified the cell adhesion protein podocalyxin expressed in a human
pluripotent stem cell, embryonal carcinoma (EC), which is a malignant germ cell …

Abstract Podocalyxin/podocalyxin-like protein 1 [PCLP1]/thrombomucin/MEP21 is a CD34-
related sialomucin. We have performed a detailed analysis of its expression during murine …

Simple Summary Malignancies derived from epithelial cells account for over 90% of all
human cancers. Several aspects of cancer progression such as metastasis, immune …

The sialoglycoprotein podocalyxin is absent in normal pancreas but is overexpressed in
pancreatic cancer and is associated with poor clinical outcome. Here, we investigate the role …

Severe pulmonary hypertension (PH) is characterized by complex precapillary arteriolar
lesions, which contain phenotypically altered smooth muscle (SM) and endothelial cells …

Selectins facilitate metastasis and tumor cell arrest in the microvasculature by mediating
binding of selectin-expressing host cells to ligands on tumor cells. We recently identified …

Podocalyxin (Podxl) has an essential role in the development and function of the kidney
glomerular filtration barrier. It is also expressed by vascular endothelia but perinatal lethality …