Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

A critical evaluation of the biological construct skeletal muscle hypertrophy: size matters but so does the measurement

CT Haun, CG Vann, BM Roberts, AD Vigotsky… - Frontiers in …, 2019 - frontiersin.org
Skeletal muscle is highly adaptable and has consistently been shown to morphologically
respond to exercise training. Skeletal muscle growth during periods of resistance training …

[HTML][HTML] An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy

C Lim, EA Nunes, BS Currier, JC Mcleod… - Medicine and science …, 2022 - ncbi.nlm.nih.gov
Skeletal muscle plays a critical role in physical function and metabolic health. Muscle is a
highly adaptable tissue that responds to resistance exercise (RE; loading) by …

Regulation of ribosome biogenesis in skeletal muscle hypertrophy

VC Figueiredo, JJ McCarthy - Physiology, 2019 - journals.physiology.org
The ribosome is the enzymatic macromolecular machine responsible for protein synthesis.
The rates of protein synthesis are primarily dependent on translational efficiency and …

[HTML][HTML] The importance of resistance exercise training to combat neuromuscular aging

KM Lavin, BM Roberts, CS Fry, T Moro… - …, 2019 - journals.physiology.org
Older adults undergoing age-related decrements in muscle health can benefit substantially
from resistance exercise training, a potent stimulus for whole muscle and myofiber …

Benefits of higher resistance‐training volume are related to ribosome biogenesis

D Hammarström, S Øfsteng, L Koll… - The Journal of …, 2020 - Wiley Online Library
Key points For individuals showing suboptimal adaptations to resistance training,
manipulation of training volume is a potential measure to facilitate responses. This remains …

Physiological differences between low versus high skeletal muscle hypertrophic responders to resistance exercise training: current perspectives and future research …

MD Roberts, CT Haun, CB Mobley… - Frontiers in …, 2018 - frontiersin.org
Numerous reports suggest there are low and high skeletal muscle hypertrophic responders
following weeks to months of structured resistance exercise training (referred to as low and …

The impact of exercise and nutrition on the regulation of skeletal muscle mass

C McGlory, S van Vliet, T Stokes… - The Journal of …, 2019 - Wiley Online Library
The maintenance of skeletal muscle mass and strength throughout life is a key determinant
of human health and well‐being. There is a gradual loss of both skeletal muscle mass and …

Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults

T Moro, CR Brightwell, DE Phalen, CF McKenna… - Experimental …, 2019 - Elsevier
Objectives Adequate muscle perfusion supports the transport of nutrients, oxygen and
hormones into muscle fibers. Aging is associated with a substantial decrease in skeletal …