Multiple sclerosis is a highly heterogeneous disease, and the detection of neuroaxonal
damage as well as its quantification is a critical step for patients. Blood-based serum …

Neuronal injury is a universal event that occurs in disease processes that affect both the
central and peripheral nervous systems. A blood biomarker linked to neuronal injury would …

Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous
system characterized by inflammatory demyelination and axonal/neuronal damage. The …

Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …

Serum neurofilament light chain (NfL) is emerging as an important biomarker in multiple
sclerosis (MS). Our objective was to evaluate the prognostic value of serum NfL levels …

The advent of highly effective disease modifying therapy has transformed the landscape of
multiple sclerosis (MS) care over the last two decades. However, there remains a critical …

Background: A limited number of studies investigated associations between serum
neurofilament light chain (sNfL) and cognition in persons with multiple sclerosis (PwMS) …

Multiple sclerosis (MS) is an immune-mediated inflammatory and degenerative disorder of
the central nervous system (CNS) with heterogeneous clinical manifestations. In the last …

Background Gray matter (GM) pathology is closely associated with physical and cognitive
impairment in persons with multiple sclerosis (PwMS). Similarly, serum neurofilament light …

Background Easily accessible biomarkers enabling the identification of those patients with
multiple sclerosis (MS) who will accumulate irreversible disability in the long term are …