[HTML][HTML] Advancing cell-based cancer immunotherapy through stem cell engineering
Advances in cell-based therapy, particularly CAR-T cell therapy, have transformed the
treatment of hematological malignancies. Although an important step forward for the field …
treatment of hematological malignancies. Although an important step forward for the field …
[HTML][HTML] Mucosal-associated invariant T cells for cancer immunotherapy
YR Li, K Zhou, M Wilson, A Kramer, Y Zhu, N Dawson… - Molecular Therapy, 2023 - cell.com
Human mucosal-associated invariant T (MAIT) cells are characterized by their expression of
an invariant TCR α chain Vα7. 2-Jα33/Jα20/Jα12 paired with a restricted TCR β chain. MAIT …
an invariant TCR α chain Vα7. 2-Jα33/Jα20/Jα12 paired with a restricted TCR β chain. MAIT …
[HTML][HTML] Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design
YR Li, CJ Ochoa, Y Zhu, A Kramer, M Wilson, Y Fang… - Iscience, 2023 - cell.com
Ovarian cancer (OC) is highly lethal due to late detection and frequent recurrence. Initial
treatments, comprising surgery and chemotherapy, lead to disease remission but are …
treatments, comprising surgery and chemotherapy, lead to disease remission but are …
The Role of Innate T Cells in Cancer
Y Chen, Y Zhu, YR Li - Handbook of Cancer and Immunology, 2023 - Springer
Innate T cells, comprising invariant natural killer T (iNKT) cells, gamma delta T (γδ T) cells,
and mucosal-associated invariant T (MAIT) cells, constitute a vital component of the immune …
and mucosal-associated invariant T (MAIT) cells, constitute a vital component of the immune …
Stem Cell-Derived Cell Therapy for Cancer
M Wilson, Z Lyu, Y Fang, YR Li - 2023 - Springer
The advent of genetic engineering strategies has transformed the landscape of cancer
immunotherapy, leading to the development and adoption of CAR-T cell therapy. However …
immunotherapy, leading to the development and adoption of CAR-T cell therapy. However …