Recent advances in genome-wide association studies have stimulated interest in the
genomic prediction of disease risk, potentially enabling individual-level risk estimates for …

Члены Комитета экспертов подтвердили отсутствие финансовой поддержки/конфликта
интересов. В случае сообщения о наличии конфликта интересов, член (ы) Комитета …

Alzheimer's disease (AD), the most common form of dementia in western societies, is a
pathologically and clinically heterogeneous disease with a strong genetic component. The …

Objective To evaluate the associations of a polygenic risk score and healthy lifestyle with
incident stroke. Design Prospective population based cohort study. Setting UK Biobank …

Aims Genetics plays an important role in coronary heart disease (CHD) but the clinical utility
of genomic risk scores (GRSs) relative to clinical risk scores, such as the Framingham Risk …

Recent genome-wide association studies in stroke have enabled the generation of genomic
risk scores (GRS) but their predictive power has been modest compared to established …

Background: Age-adjusted stroke incidence has decreased over the past 50 years, likely as
a result of changes in the prevalence and impact of various stroke risk factors. An updated …

Cerebral small vessel disease (SVD) is an important cause of stroke and cognitive
impairment among the elderly and is a more frequent cause of stroke in Asia than in the US …

Stroke is one of the most devastating pathologies of the early twenty-first century
demonstrating 1-month case-fatality rates ranging from 13 to 35% worldwide. Though the …

During the past several decades, a striking rise in the number of people with the metabolic
syndrome has taken place, associated with the global epidemics of obesity and diabetes …