Sample preparation is one of the most crucial processes in proteomics research. The results
of the experiment depend on the condition of the starting material. Therefore, the proper …

Background and Purpose—Cerebrolysin, a mixture of neurotrophic peptides, enhances
neurogenesis and improves neurological outcome in experimental neurodegenerative …

Many central nervous system (CNS) drug discovery programs require the successful
collection of cerebrospinal fluid (CSF) for assessing CNS penetration and distribution of new …

Cerebrospinal fluid (CSF) is in direct contact with the extracellular space in the central
nervous system (CNS), and biological changes in the brain can be reflected in CSF. In the …

Aims Heterocyclic pyrazole derivative has been described for the treatment of pain and
inflammatory diseases. This study evaluated the in vivo, antinociceptive, anti-inflammatory …

It has been shown that sex steroid hormones have profound neuroprotective effects in
experimental traumatic brain injury (TBI). Because the endogenous hormone levels are …

Depression, or major depressive disorder (MDD), is a widespread mental health condition
marked by enduring feelings of sorrow and loss of interest. Treatment of depression …

We are studying an endogenous, oxytocinergic analgesia system to obtain more information
about normal and pathological pain processes. In the recent years, this oxytocinergic system …

We have set out to establish a fast, simple and innocuous method for repeatedly obtaining
cerebrospinal fluid (CSF) samples from rats that are undergoing different experimental …

Kynurenic acid (KYNA) is an antagonist of ionotropic glutamate receptors, preferentially
blocking the glycine‐site of the N‐methyl‐d‐aspartate (NMDA) receptor. In the present …