The endoplasmic reticulum (ER) has a quality-control system for'proof-reading'newly
synthesized proteins, so that only native conformers reach their final destinations. Non …

The endoplasmic reticulum (ER) uses an elaborate surveillance system called the ER
quality control (ERQC) system. The ERQC facilitates folding and modification of secretory …

▪ Abstract Medical genetics so far has identified∼ 16,000 missense mutations leading to
single amino acid changes in protein sequences that are linked to human disease. A …

Yeast Saccharomyces cerevisiae has become an attractive cell factory for production of
commodity and speciality chemicals and proteins, such as industrial enzymes and …

Biotechnological innovations over the past 25 years have underpinned the rapid
development of a thriving biopharmaceutical sector. Therapeutic insulin remains one of the …

Since the first administration of insulin to a person with diabetes in 1922, scientific
contributions from academia and industry have improved insulin therapy and access. The …

The yeast Saccharomyces cerevisiae is an attractive host for the production of heterologous
proteins. However, low-yield production of many proteins (from micrograms to …

Saccharomyces cerevisiae plays an important role in the heterologous expression of an
array of proteins due to its easy manipulation, low requirements and ability for protein post …

The expression of recombinant proteins incorporated into the cell wall of Saccharomyces
cerevisiae (yeast surface display) is an important tool for protein engineering and library …

Having decided on yeast as a production host, the choice of species is often the first
question any researcher new to the field will ask. With over 500 known species of yeast to …