Enzymatic mechanisms of phosphate and sulfate transfer

WW Cleland, AC Hengge - Chemical reviews, 2006 - ACS Publications
Many biological molecules contain phosphate or sulfate, and the enzymatic reactions that
transfer these groups play important roles in metabolism. DNA and RNA are phosphate …

Recent developments in self-resistance gene directed natural product discovery

Y Yan, N Liu, Y Tang - Natural Product Reports, 2020 - pubs.rsc.org
Covering: 2000 to 2019 Natural products (NPs) are important sources of human therapeutic
agents and pesticides. To prevent self-harm from bioactive NPs, some microbial producers …

Ornithine transcarbamylase–From structure to metabolism: An update

M Couchet, C Breuillard, C Corne, J Rendu… - Frontiers in …, 2021 - frontiersin.org
Ornithine transcarbamylase (OTC; EC 2.1. 3.3) is a ubiquitous enzyme found in almost all
organisms, including vertebrates, microorganisms, and plants. Anabolic, mostly trimeric …

[图书][B] Springer Handbook of Enzymes: Class 2· Transferases XII EC 2.7. 8–2.9. 1

D Schomburg, I Schomburg, A Chang - 2008 - Springer
< 1> Canis familiaris (isozymes A and B [1])[1]< 2> Rattus norvegicus (male rats [48];
Sprague-Dawley rats [40]; ST1A1 [40, 48]; AST IV [48]; aryl sulfotransferase IV [32, 48]; a …

Targeted antibiotic discovery through biosynthesis-associated resistance determinants: Target directed genome mining

EC O'Neill, M Schorn, CB Larson… - Critical reviews in …, 2019 - Taylor & Francis
Intense competition between microbes in the environment has directed the evolution of
antibiotic production in bacteria. Humans have harnessed these natural molecules for …

Functional Characterization of the Gene Cluster from Pseudomonas syringae pv. phaseolicola NPS3121 Involved in Synthesis of Phaseolotoxin

S Aguilera, K López-López, Y Nieto… - Journal of …, 2007 - Am Soc Microbiol
Pseudomonas syringae pv. phaseolicola is the causal agent of halo blight disease of beans
(Phaseolus vulgaris L.), which is characterized by water-soaked lesions surrounded by a …

Recent advances in the synthesis and applications of phosphoramides

YY Zhu, Y Niu, YN Niu, SD Yang - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
Phosphoramide, as an important framework of many biologically active molecules, has
attracted widespread attention in recent decades. It is not only widely used in …

Enzyme active sites: Identification and prediction of function using computational chemistry

KK Barnsley, MJ Ondrechen - Current Opinion in Structural Biology, 2022 - Elsevier
Understanding the biochemically active amino acids in proteins is a key factor to improve the
knowledge of how enzymes work, to predict the function of newly discovered protein …

Scoring and lessons learned with the CSAR benchmark using an improved iterative knowledge-based scoring function

SY Huang, X Zou - Journal of chemical information and modeling, 2011 - ACS Publications
Based on a statistical mechanics-based iterative method, we have extracted a set of
distance-dependent, all-atom pairwise potentials for protein–ligand interactions from the …

Oxamic transcarbamylase of Escherichia coli is encoded by the three genes allFGH (formerly fdrA, ylbE, and ylbF)

NY Kim, OB Kim - Applied and Environmental Microbiology, 2024 - Am Soc Microbiol
Escherichia coli uses allantoin as the sole nitrogen source during anaerobic growth. In the
final step of allantoin degradation, oxamic transcarbamylase (OXTCase) converts oxalurate …