Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Tuberculosis (TB) remains one of the most widespread and leading deadliest diseases,
threats one-third of the world's population. Although numerous efforts have been undertaken …

A strategy in the discovery of anti-tuberculosis (anti-TB) drug involves targeting the enzymes
involved in the biosynthesis of Mycobacterium tuberculosis'(Mtb) cell wall. One of these …

A series of novel ethyl-7-((1-(benzyl)-1H-1, 2, 3-triazol-4-yl) methoxy)-2-oxo-2H-chromene-3-
carboxylates 8a-h as potential antifungal agents were synthesized via click chemistry. The …

Mycobacterial arabinan is a common constituent of both arabinogalactan (AG) and
lipoarabinomannan (LAM). In this study, synthesis of β-Ara f containing common arabinan …

Chloro-1, 3-dimethylimidazolinium chloride (DMC, herein also referred to as Shoda's
reagent) and its derivatives are useful for numerous synthetic transformations in which the …

A series of novel 2H-chromen-2-one derivatives decorated with 1, 2, 3-triazole moiety were
designed and synthesized using the click reaction of azidoalkyloxy-2H-chromen-2-ones with …

The concept of click chemistry represented by the formation of the 1, 2, 3-triazole core has
found wide application in drug discovery, particularly in the early discovery phases and the …

The synthesis of customized glycoconjugates constitutes a major goal for biocatalysis. To
this end, engineered glycosidases have received great attention and, among them …

A simple and efficient synthesis of modified 1, 2, 3-triazole nucleosides was developed. The
strategy involved sequential one-pot acetylation-azidation-cycloaddition procedure and was …