C Olive - Expert review of vaccines, 2012 - Taylor & Francis
The innate immune system plays an essential role in the host's first line of defense against microbial invasion, and involves the recognition of distinct pathogen-associated molecular …
JT van Dissel, SA Joosten, ST Hoff, D Soonawala… - Vaccine, 2014 - Elsevier
Here, we report on a first-in-man trial where the tuberculosis (TB) vaccine Ag85B-ESAT-6 (H1) was adjuvanted with escalating doses of a novel liposome adjuvant CAF01. On their …
Y Miyake, K Toyonaga, D Mori, S Kakuta, Y Hoshino… - Immunity, 2013 - cell.com
Cord factor, also called trehalose-6, 6′-dimycolate (TDM), is a potent mycobacterial adjuvant. We herein report that the C-type lectin MCL (also called Clec4d) is a TDM receptor …
B Mothe, A Llano, J Ibarrondo, J Zamarreno… - PloS one, 2012 - journals.plos.org
Cytotoxic T lymphocyte (CTL) responses targeting specific HIV proteins, in particular Gag, have been associated with relative control of viral replication in vivo. However, Gag-specific …
ABSTRACT T follicular helper (Tfh) cells are specialized providers of cognate B cell help, which is important in promoting the induction of high-affinity antibody production in germinal …
O Teymournejad, Z Li, P Beesetty, C Yang… - npj Vaccines, 2023 - nature.com
Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently needed. Despite a considerable promise in preclinical models, all vaccines tested thus far …
K Sen, M Mandal - International journal of pharmaceutics, 2013 - Elsevier
Recent innovations and developments in nanotechnology have revolutionized cancer therapeutics. Engineered nanomaterials are the current workhorses in the emerging field of …
KT Ryter, G Ettenger, OK Rasheed, C Buhl… - Journal of medicinal …, 2019 - ACS Publications
Mycobacterium tuberculosis (Mtb) continues to be a major health threat worldwide, and the development of Mtb vaccines could play a pivotal role in the prevention and control of this …
Self-amplifying RNA (saRNA) is well suited as a vaccine platform against chlamydia, as it is relatively affordable and scalable, has been shown to induce immunity against multivalent …