Approximately one half-century ago several classes of medications, discovered by
serendipity, were introduced for the treatment of depression and bipolar disorder. These …

Phenotypic variability and likely extensive genetic heterogeneity have been confounding the
search for the causes of schizophrenia since the inception of the diagnostic category. The …

First published in 2002. Schizophrenia: A Scientific Delusion?, first published in 1990, made
a very significant contribution to the debates on the concepts of schizophrenia and mental …

Inheritance of a defect in a neuronal mechanism that regulates response to auditory stimuli
was studied in nine families with multiple cases of schizophrenia. The defect, a decrease in …

The summaries of evidence have provided ready-made challenges to previously
unquestioned medical options... the book provides a challenging update on the nature of …

This paper describes an elementary deficit in sensory processing in people with
schizophrenia. If paired sounds are presented to normal subjects, the response to the first …

Over the course of the last 50 years many models of major depressive disorder have been
developed on the basis of theoretical aspects of this disorder. These models and procedures …

The search for genes in bipolar disorder has provided numerous genetic loci that have been
linked to susceptibility to developing the disorder. However, because of the genetic …

Schizophrenia is clinically heterogeneous but it is not known whether this is due to the
existence of discrete subtypes. For the purpose of explication,'indicators' of schizophrenia …

Eye tracking dysfunction (ETD) is one of the most widely replicated behavioral deficits in
schizophrenia and is over-represented in clinically unaffected first-degree relatives of …