Hello from the other side: how autoantibodies circumvent the blood–brain barrier in autoimmune encephalitis

MP Platt, D Agalliu, T Cutforth - Frontiers in immunology, 2017 - frontiersin.org
Antibodies against neuronal receptors and synaptic proteins are associated with
autoimmune encephalitides (AE) that produce movement and psychiatric disorders. In order …

CNS autoimmune disease after Streptococcus pyogenes infections: animal models, cellular mechanisms and genetic factors

T Cutforth, MMC DeMille, I Agalliu, D Agalliu - Future neurology, 2016 - Taylor & Francis
Streptococcus pyogenes infections have been associated with two autoimmune diseases of
the CNS: Sydenham's chorea (SC) and pediatric autoimmune neuropsychiatric disorders …

Effect of early and prophylactic nonsteroidal anti-inflammatory drugs on flare duration in pediatric acute-onset neuropsychiatric syndrome: an observational study of …

KD Brown, C Farmer, GM Freeman Jr… - Journal of child and …, 2017 - liebertpub.com
Abstract Introduction: Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is
characterized by the sudden onset of severe obsessive-compulsive symptoms and/or eating …

Pediatric acute-onset neuropsychiatric syndrome response to oral corticosteroid bursts: an observational study of patients in an academic community-based PANS …

K Brown, C Farmer, B Farhadian… - Journal of child and …, 2017 - liebertpub.com
Background: Sudden-onset severe obsessive-compulsive symptoms and/or severely
restrictive food intake with at least two coinciding, similarly debilitating neuropsychiatric …

Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness

F Zoratto, M Sbriccoli, A Martinelli, JC Glennon… - …, 2018 - Elsevier
Deficits in empathy, the ability to share an emotion of another individual, constitute a
hallmark of several psychopathological conditions, including conduct disorder. The co …

The psychopharmacology of obsessive-compulsive disorder: a preclinical roadmap

H Szechtman, BH Harvey, EZ Woody, KL Hoffman… - Pharmacological …, 2020 - Elsevier
This review evaluates current knowledge about obsessive-compulsive disorder (OCD), with
the goal of providing a roadmap for future directions in research on the …

Low empathy-like behaviour in male mice associates with impaired sociability, emotional memory, physiological stress reactivity and variations in neurobiological …

G Laviola, F Zoratto, D Ingiosi, V Carito, D Huzard… - PloS one, 2017 - journals.plos.org
Deficits in empathy have been proposed to constitute a hallmark of several psychiatric
disturbances like conduct disorder, antisocial and narcissistic personality disorders. Limited …

Characterization of an experimental model to determine streptococcal M protein–induced autoimmune cardiac and neurobehavioral abnormalities

RAM Rafeek, AS Hamlin… - … and Cell Biology, 2022 - Wiley Online Library
Group A streptococcal (GAS) infection is associated with a spectrum of autoimmune
diseases including acute rheumatic fever/rheumatic heart disease (ARF/RHD) and …

Maternal immune activation in mice only partially recapitulates the autism spectrum disorders symptomatology

D Vigli, G Palombelli, S Fanelli, G Calamandrei… - Neuroscience, 2020 - Elsevier
Prenatal viral/bacterial infections are considered risk factors for autism spectrum disorders
(ASD) and rodent models of maternal immune activation (MIA) have been developed and …

Course of neuropsychiatric symptoms after introduction and removal of nonsteroidal anti-inflammatory drugs: a pediatric observational study

EJ Spartz, GM Freeman Jr, K Brown… - Journal of Child and …, 2017 - liebertpub.com
Objective: Accumulating evidence suggests that anti-inflammatory interventions can
modulate neuropsychiatric symptoms. Pediatric Acute-onset Neuropsychiatric Syndrome …