Aberrant expression, function, and mutation of G protein-coupled receptors (GPCRs) and
their signaling partners, G proteins, have been well documented in many forms of cancer …

Graphical Abstract Abstract Alterations in the homeostasis of several adhesion GPCRs
(aGPCRs) have been observed in cancer. The main cellular functions regulated by aGPCRs …

Breast cancer brain metastases (BCBMs) are common in patients with metastatic breast
cancer and indicate a poor prognosis. These tumors are especially resistant to currently …

The vimentin network displays remarkable plasticity to support basic cellular functions and
reorganizes during cell division. Here, we show that in several cell types vimentin filaments …

Engineered oncolytic viruses are used clinically to destroy cancer cells and have the ability
to boost anticancer immunity. Phosphatase and tensin homolog deleted on chromosome 10 …

Spatially resolved transcriptomics technologies enable comprehensive measurement of
gene expression patterns in the context of intact tissues. However, existing technologies …

Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in
cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is …

Background: The efferocytosis-related molecules have been considered to be correlated
with the resistance to cancer chemotherapy. The aim of this study was to investigate the …

Introduction The G protein-coupled receptors (GPCR) superfamily is among the most widely
exploited targets for therapeutics, with drugs mainly targeting the Rhodopsin, Glutamate and …

Nestin is a member of the intermediate filament family, which is expressed in a variety of
stem or progenitor cells as well as in several types of malignancies. Nestin might be …