Prevalence of HIV-1 subtypes among men who have sex with men in China: a systematic review

L Zhang, Y Wang, B Wang, J Yan… - … journal of STD & …, 2015 - journals.sagepub.com
The distribution of prevalent HIV-1 strains are still complex in China. Men who have sex with
men (MSM) play an important bridging role in spreading HIV. The aim of our study was to …

Trends in pretreatment HIV-1 drug resistance in antiretroviral therapy-naive adults in South Africa, 2000–2016: a pooled sequence analysis

B Chimukangara, RJ Lessells, SY Rhee… - …, 2019 - thelancet.com
Abstract Background South Africa has the largest public antiretroviral therapy (ART)
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …

Current computational approaches for the development of anti-HIV inhibitors: an overview

U Panwar, I Chandra, C Selvaraj… - Current pharmaceutical …, 2019 - ingentaconnect.com
Background: Today, HIV-1 infection has become an extensive problem to public health and
a greater challenge to all working researchers throughout the world. Since the beginning of …

Genetic and antiretroviral drug resistance mutations analysis of reverse transcriptase and protease gene from Pakistani people living with HIV-1

D Siddiqui, U Badar, M Javaid, N Farooqui, SA Shah… - PLoS …, 2023 - journals.plos.org
Background Antiretroviral therapy (ART) effectiveness is compromised by the emergence of
HIV drug resistance mutations (DRM) and can lead to the failure of ART. Apart from intrinsic …

Moderate levels of pre-treatment HIV-1 antiretroviral drug resistance detected in the first South African National Survey

K Steegen, S Carmona, M Bronze… - PloS one, 2016 - journals.plos.org
Background In order to assess the level of transmitted and/or pre-treatment antiretroviral
drug resistance to HIV-1, the World Health Organization (WHO) recommends that regular …

Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa

D Brado, AE Obasa, GM Ikomey, R Cloete, K Singh… - Scientific reports, 2018 - nature.com
HIV-Integrase (IN) has proven to be a viable target for highly specific HIV-1 therapy. We
aimed to characterize the HIV-1 IN gene in a South African context and identify resistance …

In-depth analysis of HIV-1 drug resistance mutations in HIV-infected individuals failing first-line regimens in West and Central Africa

CJ Villabona-Arenas, N Vidal, E Guichet, L Serrano… - Aids, 2016 - journals.lww.com
Objective: In resource-limited countries, antiretroviral therapy (ART) has been scaled up, but
individual monitoring is still suboptimal. Here, we studied whether or not ART had an impact …

Spatial–temporal transmission dynamics of HIV-1 CRF01_AE in Indonesia

SQ Khairunisa, DW Indriati, NLA Megasari, S Ueda… - Scientific Reports, 2024 - nature.com
Human immunodeficiency virus type 1 (HIV-1) remains a serious health threat in Indonesia.
In particular, the CRF01_AE viruses were the predominant HIV-1 strains in various cities in …

Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: a narrative overview

PO Bessong, ND Matume, DM Tebit - AIDS Research and Therapy, 2021 - Springer
Abstract Background South Africa, with one of the highest HIV prevalences in the world,
introduced the universal test and treat (UTT) programme in September 2016. Barriers to …

Near-full-length genome analysis of a HIV-1 CRF01_AE/B recombinant strain among men who have sex with men in Chengde City, China

S Dong, X Lu, Y Wang, N An, M Liu, Y Li… - AIDS Research and …, 2024 - liebertpub.com
The unique recombinant form (URF) of HIV is formed by multiple subtypes which are
cocirculating in some area, and the number of HIV recombinants is on the increase …