Genetically encoded fluorescent biosensors illuminate the spatiotemporal regulation of signaling networks

EC Greenwald, S Mehta, J Zhang - Chemical reviews, 2018 - ACS Publications
Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

A mitochondria-targeted fluorescent probe for ratiometric detection of hypochlorite in living cells

Y Chen, T Wei, Z Zhang, W Zhang, J Lv, T Chen… - Chinese Chemical …, 2017 - Elsevier
Hypochlorous acid (HOCl) plays a vital role in many physiological and pathological
processes as one of reactive oxygen species (ROS). Developing highly sensitive and …

Engineering voltage sensing phosphatase (VSP)

H Tsutsui, N Mizutani, Y Okamura - Methods in Enzymology, 2021 - Elsevier
Voltage sensing phosphatase (VSP), consists of a voltage sensor domain (VSD) like that
found in voltage-gated ion channels and a phosphoinositide (PIP) phosphatase region …

Engineering photoactivatability in genetically encoded voltage and pH indicators

S Lee, YK Song, BJ Baker - Frontiers in Cellular Neuroscience, 2019 - frontiersin.org
Genetically-encoded indicators of neuronal activity enable the labeling of a genetically
defined population of neurons to optically monitor their activities. However, researchers …

[PDF][PDF] Разработка индикатора мембранного потенциала на основе красного флуоресцентного белка FusionRed

ЛА Кост - ibch.ru
В настоящее время применяется ряд подходов для регистрации электрической
активности множества клеток одновременно. Это необходимо для изучения …

Chemigenetic voltage indicators

ER Schreiter, LD Lavis, A Abdelfattah - 2018 - Google Patents
Provided herein are a voltage indicator and a method of measuring voltage. The voltage
indicator includes a membrane-localized voltage-sensitive protein coupled to a capture …

Chemigenetic voltage indicators

ER Schreiter, LD Lavis, A Abdelfattah - US Patent App. 17/835,535, 2022 - Google Patents
Provided herein are a voltage indicator and a method of measuring voltage. The voltage
indicator includes a membrane-localized voltage-sensitive protein coupled to a capture …

Chemigenetic voltage indicators

ER Schreiter, LD Lavis, A Abdelfattah - US Patent 11,385,236, 2022 - Google Patents
Provided herein are a voltage indicator and a method of measuring voltage. The voltage
indicator includes a membrane-localized voltage-sensitive protein coupled to a capture …

All-Optical Neurophysiology in the 1-Photon Regime

SL Farhi - 2018 - search.proquest.com
Simultaneous optical recording and optical stimulation of neuronal activity could enable
faster and more comprehensive investigation of neuronal function but is hampered by …