Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery

J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang… - Bioorganic …, 2022 - Elsevier
Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

CRISPR/Cas genome editing to optimize pharmacologically active plant natural products

A Dey - Pharmacological Research, 2021 - Elsevier
Since time immemorial, human use medicinal plants as sources of food, therapy and
industrial purpose. Classical biotechnology and recent next-generation sequencing (NGS) …

Biosynthesis and Regulatory Mechanisms of Bioactive Compounds in Salvia miltiorrhiza, a Model System for Medicinal Plant Biology

S Lu - Critical Reviews in Plant Sciences, 2021 - Taylor & Francis
Salvia miltiorrhiza is one of the most well known species in the genus Salvia of the
Lamiaceae with great economic, academic and medicinal value. It was recorded as a …

Antiproliferative abietane quinone diterpenoids from the roots of Salvia deserta

X Zheng, A Kadir, G Zheng, P Jin, D Qin… - Bioorganic …, 2020 - Elsevier
A total of twenty abietane quinone diterpenoids including ten new ones (1–10) were isolated
from the roots extract of Salvia deserta. Their chemical structures were delineated by …

Structurally Diverse Diterpenoids from the Roots of Salvia deserta Based on Nine Different Skeletal Types

A Kadir, G Zheng, X Zheng, P Jin… - Journal of Natural …, 2021 - ACS Publications
Twenty-four diterpenoids (1–24), classified into nine diverse carbon skeletal types, 8-nor-7
(8→ 14), 9 (8→ 7)-di-abeo-abietane (1, 2, and 13), 7 (8→ 14), 9 (8→ 7)-di-abeo-abietane (3 …

Abietane‐Type Diterpenoids: Insights into Structural Diversity and Therapeutic Potential

Z Sargazifar, D Ghorbanian Charami… - Chemistry & …, 2024 - Wiley Online Library
The abietane‐type diterpenoids are among the most significant diterpene subsets found in
hundreds of plant species belonging to various families. Among which, the members of the …

The mixture of Agrimonia pilosa Ledeb. and Salvia miltiorrhiza Bunge. extract produces analgesic and anti-inflammatory effects in a collagen-induced arthritis mouse …

JH Feng, JS Jung, SH Hwang, SK Lee… - Animal Cells and …, 2022 - Taylor & Francis
Pain and inflammation typically manifest in patients with arthritis. It is now widely known that
Agrimonia pilosa Ledeb (AP) and Salvia miltiorrhiza Bunge (SM) exert anti-inflammatory and …

The Anti-Inflammatory and the Antinociceptive Effects of Mixed Agrimonia pilosa Ledeb. and Salvia miltiorrhiza Bunge Extract

JH Feng, HY Kim, SM Sim, GL Zuo, JS Jung… - Plants, 2021 - mdpi.com
Arthritis is a common condition that causes pain and inflammation in a joint. Previously, we
reported that the mixture extract (ME) from Agrimonia pilosa Ledeb.(AP) and Salvia …

Structural characterisation and antioxidant activities in vitro and in vivo of a novel polysaccharide from Salvia miltiorrhiza

Y Jing, J Hu, Z Su, W Cheng, Y Zhang… - Natural Product …, 2023 - Taylor & Francis
Polysaccharides have received extensive attention due to their multiple physiological
functions, especially their remarkable antioxidant capacity. In this study, a novel acidic …

Highly oxygenated germacrane-type sesquiterpenoids from the whole plant of Salvia cavaleriei H. Lév. and their biological activities

XH Chen, X Liu, WB Cui, FL An, L Liu, Q Wu, JN Yu… - Phytochemistry, 2023 - Elsevier
The entire plant Salvia cavaleriei H. Lév.(Lamiaceae) is used as a traditional Chinese herbal
medicine. Its leaves are edible, and the flowers can be soaked in water to make a health …