Clinical prediction models in psychiatry: a systematic review of two decades of progress and challenges

AJ Meehan, SJ Lewis, S Fazel, P Fusar-Poli… - Molecular …, 2022 - nature.com
Recent years have seen the rapid proliferation of clinical prediction models aiming to
support risk stratification and individualized care within psychiatry. Despite growing interest …

Cognitive deficits in psychotic disorders: a lifespan perspective

JM Sheffield, NR Karcher, DM Barch - Neuropsychology review, 2018 - Springer
Individuals with disorders that include psychotic symptoms (ie psychotic disorders)
experience broad cognitive impairments in the chronic state, indicating a dimension of …

Prediction models of functional outcomes for individuals in the clinical high-risk state for psychosis or with recent-onset depression: a multimodal, multisite machine …

N Koutsouleris, L Kambeitz-Ilankovic… - JAMA …, 2018 - jamanetwork.com
Importance Social and occupational impairments contribute to the burden of psychosis and
depression. There is a need for risk stratification tools to inform personalized functional …

Annual Research Review: Prevention of psychosis in adolescents–systematic review and meta‐analysis of advances in detection, prognosis and intervention

A Catalan, G Salazar de Pablo… - Journal of Child …, 2021 - Wiley Online Library
Background The clinical high‐risk state for psychosis (CHR‐P) paradigm has facilitated the
implementation of psychosis prevention into clinical practice; however, advancements in …

European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia

A Vita, W Gaebel, A Mucci, G Sachs, A Erfurth… - European …, 2022 - cambridge.org
Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …

Annual Research Review: The contributions of the RDoC research framework on understanding the neurodevelopmental origins, progression and treatment of mental …

J Pacheco, MA Garvey, CS Sarampote… - Journal of Child …, 2022 - Wiley Online Library
The National Institute of Mental Health (NIMH) proposed the Research Domain Criteria
(RDoC) initiative as an alternate way to organize research of mental illnesses, by looking at …

EPA guidance on the early detection of clinical high risk states of psychoses

F Schultze-Lutter, C Michel, SJ Schmidt… - European …, 2015 - cambridge.org
The aim of this guidance paper of the European Psychiatric Association is to provide
evidence-based recommendations on the early detection of a clinical high risk (CHR) for …

A critique of the “ultra‐high risk” and “transition” paradigm

J Van Os, S Guloksuz - World Psychiatry, 2017 - Wiley Online Library
The transdiagnostic expression of psychotic experiences in common mental disorder
(anxiety/depression/substance use disorder) is associated with a poorer prognosis, and a …

EPA guidance on the early intervention in clinical high risk states of psychoses

SJ Schmidt, F Schultze-Lutter… - European …, 2015 - cambridge.org
This guidance paper from the European Psychiatric Association (EPA) aims to provide
evidence-based recommendations on early intervention in clinical high risk (CHR) states of …

Early intervention service systems for youth mental health: integrating pluripotentiality, clinical staging, and transdiagnostic lessons from early psychosis

JL Shah, N Jones, J van Os, PD McGorry… - The Lancet …, 2022 - thelancet.com
Challenges associated with operationalising services for the at-risk mental state for
psychosis solely in that same diagnostic silo are increasingly well recognised—namely, the …