Removal of soluble ACE2 in VeroE6 cells by 17β-estradiol reduces SARS-CoV-2 infectivity

Y Kyosei, T Yoshimura, E Ito - Biological and Pharmaceutical Bulletin, 2023 - jstage.jst.go.jp
Women are less susceptible than men to coronavirus disease 2019 (COVID-19), which
might be due to the female steroid hormone 17β-estradiol. We hypothesized that 17β …

In silico evidence that substitution of glycine for valine (p. G8V) in a common variant of TMPRSS2 isoform 1 increases accessibility to an endocytic signal: Implication …

M Calcagnile, F Damiano, G Lobreglio, L Siculella… - Biochimie, 2024 - Elsevier
The TMPRSS2 protease plays a key role in the entry of the SARS-CoV-2 into cells. The
TMPRSS2 gene is highly polymorphic in humans, and some polymorphisms may affect the …

GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma

Y Yang, Y Wang, H Zou, Z Li, W Chen… - Frontiers in …, 2024 - frontiersin.org
Background Sex hormones and their related receptors have been reported to impact the
development and progression of tumors. However, their influence on the composition and …

Effects of Combined Treatment with Sodium Dichloroacetate and Sodium Valproate on the Genes in Inflammation-and Immune-Related Pathways in T Lymphocytes …

D Stakišaitis, L Kapočius, V Tatarūnas, D Gečys… - Pharmaceutics, 2024 - mdpi.com
The study presents data on the anti-inflammatory effects of a combination of sodium
dichloroacetate and sodium valproate (DCA–VPA) on the expression of inflammation-and …

Impact of the COVID-19 pandemic and vaccination on global, regional, and national burden of Guillain-Barre syndrome: observational study

X Gao, C Zhao, J Yang, Z Yang, J Feng, S Zhan, D Fan… - medRxiv, 2024 - medrxiv.org
Objectives: To estimate the global, regional, and national burden and trends of Guillain-
Barre Syndrome (GBS), and to explore the impact of the COVID-19 pandemic and related …

Impact of patient characteristics and surgery-related risk factors on endophthalmitis after cataract surgery: a meta-analysis

S Zhang, J Xu - Ophthalmic Research, 2025 - karger.com
Introduction Cataracts are the leading cause of blindness worldwide, with a notably high
incidence rate. Endophthalmitis is the most severe complication following cataract surgery …

Epidemiological profile of patients diagnosed with covid-19 in the municipality of Sao Goncalo, Rio de Janeiro, Brazil

RR das Chagas, HR Freitas, SV Cardozo - medRxiv, 2024 - medrxiv.org
Objectives: The global health crisis caused by SARS-CoV-2 has led to over 760 million
confirmed cases and 6.8 million deaths worldwide, primarily impacting the respiratory …

Comparative analysis of CT outcomes in Covid-19: Non-Vaccinated Individuals Vs. Vaccine Break Through Cases

A Gadwal, V Poornima, GP Norhona… - CME Journal of …, 2024 - wecmelive.com
Background: In the context of the COVID-19 pandemic, this study investigates the influence
of vaccination on patient demographics and clinical outcomes. Exploring disparities aids in …

[引用][C] Establishment of aged animal models for SARS-CoV-2 research

K Wirz - 2024 - Dissertation, Hannover, Tierärztliche …

新型コロナウイルス抗原に対する超高感度検出と17β-エストラジオールによる感染減少の解明

教誓祐太 - 2023 - waseda.repo.nii.ac.jp
新型コロナウイルス感染症 (COVID-19) は 2019 年に中国で確認されてから数年が経過してなお,
世界中で感染者を出している強力なウイルスである. このウイルスにおいて最も一般的な検出法は …