Objective: The aim was to provide guidelines for evaluation, treatment, and genetic testing
for multiple endocrine neoplasia type 1 (MEN1). Participants: The group, which comprised …

Multiple endocrine neoplasia (MEN) is characterized by the occurrence of tumors involving
two or more endocrine glands within a single patient. Four major forms of MEN, which are …

Multiple endocrine neoplasia type 1 (MEN1) is classically characterized by the development
of functional or nonfunctional hyperplasia or tumors in endocrine tissues (parathyroid …

Elevated C-terminal fibroblast growth factor 23 (C-FGF23) concentrations have been
reported in Gambian children with and without putative Ca-deficiency rickets. The aims of …

In patients with multiple endocrine neoplasia type 1 (MEN1), the most common functional
pancreatic endocrine tumor (PET) syndrome is Zollinger-Ellison syndrome (ZES). ZES has …

Multiple Endocrine Neoplasia type 1 (MEN1) is an autosomal-dominant disorder
characterised by the occurrence of tumours of the parathyroids, pancreas and anterior …

Growth hormone (GH)-secreting pituitary tumours represent the most genetically determined
pituitary tumour type. This is true both for germline and somatic mutations. Germline …

Mutations of the multiple endocrine neoplasia type 1 (MEN1) gene lead to loss of function of
its protein product menin. In keeping with its tumor suppressor function in endocrine tissues …

Multiple endocrine neoplasm type 1 (MEN1) is associated with parathyroid, pancreatic, and
pituitary tumors. Although most patients present with hyperparathyroidism, the diagnosis can …

MEN 1 is a rare hereditary cancer syndrome which manifests a variety of endocrine and non-
endocrine neoplasms and lesions. Growing knowledge of this condition in both its molecular …