Cancer stem cells (CSCs), which have the potential for self-renewal, differentiation and de-
differentiation, undergo epigenetic, epithelial-mesenchymal, immunological and metabolic …

Abstract Nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) regulates the basal and stress-
inducible expression of a battery of genes encoding key components of the glutathione …

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

Nrf2 is a transcription factor that stimulates the expression of genes which have antioxidant
response element-like sequences in their promoter. Nrf2 is a cellular protector, and this …

Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …

Abstract Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a master regulator of cellular
homeostasis that controls the expression of more than 1% of human genes related to …

Neurodegenerative diseases are linked to the accumulation of specific protein aggregates,
suggesting an intimate connection between injured brain and loss of proteostasis …

Canonical WNT signaling through Frizzled and LRP5/6 receptors is transduced to the
WNT/β-catenin and WNT/stabilization of proteins (STOP) signaling cascades to regulate cell …

Oxidative stress and inflammation play an important role in the pathophysiological changes
of liver diseases. Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor …

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow
limitation and abnormal inflammatory response. Wnt/β‐catenin and AMP‐activated protein …