The 2023 impact of inflammatory bowel disease in Canada: epidemiology of IBD

S Coward, EI Benchimol, ME Kuenzig… - Journal of the …, 2023 - academic.oup.com
Inflammatory bowel disease (IBD), consisting of Crohn's disease and ulcerative colitis, is
recognized across the world, though Canada has among the highest burdens of IBD in the …

Prediction and prevention of inflammatory bowel disease

EW Lopes, W Turpin, K Croitoru, JF Colombel… - Clinical …, 2024 - Elsevier
11 Acknowledgement: We would like to thank the Helmsley Charitable Trust for their
generous 12 support of the PROMISE consortium (PRediction and PRevention through …

Early subclinical stages of the inflammatory bowel diseases: insights from human and animal studies

C Kelly, RB Sartor, JF Rawls - American Journal of …, 2025 - journals.physiology.org
The inflammatory bowel diseases (IBD) occur in genetically susceptible individuals that
mount inappropriate immune responses to their microbiota leading to chronic intestinal …

Evidence challenging the causal role of gut microbiota in inflammatory bowel diseases

N Jiao, X Ke, L Zhu, R Zhu - Gastroenterology Report, 2023 - academic.oup.com
Recently, Bourgonje et al.[1] investigated the antibody epitope repertoire in patients with
inflammatory bowel diseases (IBD)[1]. Using the high-throughput phage-display …

Crohn's patients and healthy infants share immunodominant B cell response to commensal flagellin peptide epitopes

Q Zhao, LW Duck, JT Killian Jr, AF Rosenberg… - Gastroenterology, 2024 - Elsevier
Background & Aims Inflammatory bowel disease (IBD) is a chronic manifestation of
dysregulated immune response to the gut microbiota in genetically predisposed hosts …

Fecal calprotectin level is nonlinearly associated with GI pathogen detection in patients with and without inflammatory bowel disease

KL Newman, PDR Higgins - Journal of Clinical Microbiology, 2023 - Am Soc Microbiol
Fecal calprotectin (FCP) is used to monitor inflammatory bowel disease (IBD) activity and
can also be elevated in gastrointestinal infections. Our study's objective was to quantify the …

Understanding Predictors of Crohn's Disease: Determinants of Altered Barrier Function in Pre-Disease Phase of Crohn's Disease

A Neustaeter, H Leibovitzh, W Turpin… - Journal of the …, 2024 - academic.oup.com
The pathogenesis of Crohn's disease (CD) remains unknown. The current working theory is
that genetic susceptibility influences host–microbe interactions, resulting in chronic …

Incidentally Diagnosed Asymptomatic Crohn's Disease: A Retrospective Cohort Study of Long-Term Clinical Outcomes

A Grinman, B Ungar, A Lahat, U Kopylov… - Crohn's & Colitis …, 2022 - academic.oup.com
Background Crohn's disease (CD) is occasionally diagnosed in asymptomatic patients who
have undergone colonoscopy or imaging for other reasons. The clinical outcome and …

[PDF][PDF] Incidentally diagnosed asymptomatic Crohn's disease: A retrospective cohort study of long-term clinical outcomes

R Eliakim, S Ben-Horin - 2022 - scholar.archive.org
Crohn's disease is occasionally diagnosed in asymptomatic patients who have undergone
colonoscopy or imaging for other reasons. In this study the majority of these patients without …