Left atrial cardiomyopathy–a challenging diagnosis

F Kreimer, M Gotzmann - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Left atrial cardiomyopathy (LACM) has been an ongoing focus of research for several years.
There is evidence that LACM is responsible for atrial fibrillation and embolic strokes of …

Heart failure with preserved ejection fraction: The pathophysiological mechanisms behind the clinical phenotypes and the therapeutic approach

L Stoicescu, D Crişan, C Morgovan, L Avram… - International Journal of …, 2024 - mdpi.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is an increasingly frequent form
and is estimated to be the dominant form of HF. On the other hand, HFpEF is a syndrome …

[HTML][HTML] Plasma proteomic changes in response to exercise training are associated with cardiorespiratory fitness adaptations

JM Robbins, P Rao, S Deng, MJ Keyes, UA Tahir… - JCI insight, 2023 - ncbi.nlm.nih.gov
Regular exercise leads to widespread salutary effects, and there is increasing recognition
that exercise-stimulated circulating proteins can impart health benefits. Despite this, limited …

Prognostic value of left atrial strain in aortic stenosis: a competing risk analysis

ESJ Tan, X Jin, YY Oon, SP Chan, L Gong… - Journal of the American …, 2023 - Elsevier
Background The role of left atrial (LA) strain as an imaging biomarker in aortic stenosis is not
well established. The aim of this study was to investigate the prognostic performance of …

Intersection of atrial fibrillation and heart failure with mildly reduced and preserved ejection fraction in> 400 000 participants in the Get With The Guidelines‐Heart …

RB Patel, SJ Greene, H Xu, B Alhanti… - European journal of …, 2023 - Wiley Online Library
Aims Although atrial fibrillation (AF) frequently coexists with heart failure with preserved
ejection fraction (HFpEF), few data are available evaluating AF‐specific care patterns and …

Atrial fibrillation burden and atrial shunt therapy in heart failure with preserved ejection fraction

RB Patel, VY Reddy, J Komtebedde, SW Wegerich… - Heart Failure, 2023 - jacc.org
Background Atrial fibrillation (AF) is a common comorbidity in patients with heart failure with
preserved ejection fraction (HFpEF) and in heart failure with mildly reduced ejection fraction …

Left atrial myopathy in atrial fibrillation and heart failure: clinical implications, mechanisms, and therapeutic targets

G Peigh, SJ Shah, RB Patel - Current heart failure reports, 2021 - Springer
Abstract Purpose of Review This review discusses the mechanisms, clinical implications,
and treatments of left atrial (LA) myopathy in comorbid atrial fibrillation (AF) and heart failure …

The future of heart failure with preserved ejection fraction: Deep phenotyping for targeted therapeutics

FR Heinzel, SJ Shah - Herz, 2022 - Springer
Heart failure (HF) with preserved ejection fraction (HFpEF) is a multi-organ, systemic
syndrome that involves multiple cardiac and extracardiac pathophysiologic abnormalities …

Real-time cardiovascular magnetic resonance imaging for non-invasive characterisation of heart failure with preserved ejection fraction: final outcomes of the HFpEF …

SJ Backhaus, A Schulz, T Lange… - Clinical Research in …, 2024 - Springer
Background The diagnosis of heart failure with preserved ejection fraction (HFpEF) remains
challenging. Recently, the HFpEF Stress Trial demonstrated feasibility and accuracy of non …

How to diagnose heart failure with preserved ejection fraction

S Istratoaie, L Gargani, BA Popescu… - European Heart …, 2024 - academic.oup.com
Heart failure with preserved ejection fraction (HFpEF) is a major healthcare problem that is
raising in prevalence. There has been a shift in HpEF management towards early diagnosis …