Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)

PA McCullough, PE Alexander… - Reviews in …, 2020 - scholarlycommons.henryford.com
The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness,
hospitalizations, and death. The complex and multifaceted pathophysiology of life …

Quercetin in the prevention and treatment of coronavirus infections: a focus on SARS-CoV-2

A Gasmi, PK Mujawdiya, R Lysiuk, M Shanaida… - Pharmaceuticals, 2022 - mdpi.com
The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium
due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the …

Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights

S Ali, M Alam, F Khatoon, U Fatima, AM Elasbali… - Biomedicine & …, 2022 - Elsevier
The unexpected emergence of the new Coronavirus disease (COVID-19) has affected more
than three hundred million individuals and resulted in more than five million deaths …

Discovery of METTL3 small molecule inhibitors by virtual screening of natural products

Y Du, Y Yuan, L Xu, F Zhao, W Wang, Y Xu… - Frontiers in …, 2022 - frontiersin.org
N6-Methyladenosine (m6A) is the most prevalent mRNA modification in mammalian cells
that is mainly catalyzed by the methyltransferase complex of methyltransferase-like 3 and …

Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS‐CoV‐2

A Gour, D Manhas, S Bag, B Gorain… - Phytotherapy …, 2021 - Wiley Online Library
Emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection,
COVID‐19, has become the global panic since December 2019, which urges the global …

Inhibition of SARS CoV envelope protein by flavonoids and classical viroporin inhibitors

U Breitinger, NKM Ali, H Sticht… - Frontiers in microbiology, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus (SARS-CoV), an enveloped single-stranded
positive-sense RNA virus, is a member of the genus Betacoronavirus, family Coronaviridae …

Natural polyphenols as immunomodulators to rescue immune response homeostasis: Quercetin as a research model against severe COVID-19

R Bernini, F Velotti - Molecules, 2021 - mdpi.com
The COVID-19 pandemic is caused by SARS-CoV-2 and is leading to the worst health crisis
of this century. It emerged in China during late 2019 and rapidly spread all over the world …

[HTML][HTML] Jinhua Qinggan Granule UHPLC-Q-extractive-Orbitrap-MS assay: putative identification of 45 potential anti-Covid-19 constituents, confidential addition, and …

J Zeng, X Li, R Cai, C Li, S Chen - Journal of Food and Drug …, 2023 - ncbi.nlm.nih.gov
The study combined UHPLC-Q-Orbitrap-MS analysis with authentic standards, to create a
novel strategy for isomers recognition and putative identification. Through the strategy, anti …

Quercetin: a potential candidate for the treatment of arthritis

A Goyal, N Agrawal - Current Molecular Medicine, 2022 - ingentaconnect.com
Diet plays a significant role in ensuring healthy life, and the bioactive compounds present in
food and medicinal plants may be developed as drugs that combat various illnesses. A …

Emerging Therapeutic Potential of Polyphenols from Geranium sanguineum L. in Viral Infections, Including SARS-CoV-2

S Abarova, R Alexova, S Dragomanova, A Solak… - Biomolecules, 2024 - mdpi.com
The existing literature supports the anti-inflammatory, antioxidant, and antiviral capacities of
the polyphenol extracts derived from Geranium sanguineum L. These extracts exhibit …