ST Cheng - Current psychiatry reports, 2016 - Springer
Abstract Purpose of Review The article discusses the two most significant modifiable risk factors for dementia, namely, physical inactivity and lack of stimulating cognitive activity, and …
Adult hippocampal neurogenesis plays a critical role in memory and emotion processing, and this process is dynamically regulated by neural circuit activity. However, it remains …
Adult-born granule cells (abGCs) have been implicated in cognition and mood; however, it remains unknown how these cells behave in vivo. Here, we have used two-photon calcium …
J Basu, SA Siegelbaum - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Synaptic plasticity serves as a cellular substrate for information storage in the central nervous system. The entorhinal cortex (EC) and hippocampus are interconnected brain …
The generalization of fear is an adaptive, behavioral, and physiological response to the likelihood of threat in the environment. In contrast, the overgeneralization of fear, a cardinal …
Background: The hippocampus is one of the sites in the mammalian brain that is capable of continuously generating controversy. Adult neurogenesis is a remarkable process, and yet …
Developing granule cells (GCs) of the adult dentate gyrus undergo a critical period of enhanced activity and synaptic plasticity before becoming mature. The impact of developing …
Robust incorporation of new principal cells into pre‐existing circuitry in the adult mammalian brain is unique to the hippocampal dentate gyrus (DG). We asked if adult‐born granule cells …
N Forte, S Boccella, L Tunisi… - Nature …, 2021 - nature.com
The mammalian brain stores and distinguishes among episodic memories, ie memories formed during the personal experience, through a mechanism of pattern separation …