Object recognition memory: neurobiological mechanisms of encoding, consolidation and retrieval

BD Winters, LM Saksida, TJ Bussey - Neuroscience & Biobehavioral …, 2008 - Elsevier
Tests of object recognition memory, or the judgment of the prior occurrence of an object,
have made substantial contributions to our understanding of the nature and neurobiological …

Muscarinic receptor pharmacology and circuitry for the modulation of cognition

M Bubser, N Byun, MR Wood, CK Jones - Muscarinic receptors, 2012 - Springer
The muscarinic cholinergic system constitutes an important part of the neuronal circuitry that
modulates normal cognition. Muscarinic receptor antagonists are well known to produce or …

Transient inactivation of perirhinal cortex disrupts encoding, retrieval, and consolidation of object recognition memory

BD Winters, TJ Bussey - Journal of Neuroscience, 2005 - Soc Neuroscience
Damage to perirhinal cortex (PRh) impairs object recognition memory in humans, monkeys,
and rats when tested in tasks such as delayed nonmatching to sample, visual paired …

Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety

N Pitsikas, A Boultadakis, G Georgiadou, PA Tarantilis… - Phytomedicine, 2008 - Elsevier
Crocus sativus L. is a plant cultivated in various parts of the world. Crocins are among the
active components of Crocus sativus L. The present study was designed to investigate in the …

Dysregulated hippocampal acetylcholine neurotransmission and impaired cognition in M2, M4 and M2/M4 muscarinic receptor knockout mice

ET Tzavara, FP Bymaster, CC Felder, M Wade… - Molecular …, 2003 - nature.com
Among the five different muscarinic receptors that have been cloned and characterized, M2
and M4 receptors are localized both post-and presynaptically and are believed to have a …

Removal of cholinergic input to perirhinal cortex disrupts object recognition but not spatial working memory in the rat

BD Winters, TJ Bussey - European Journal of Neuroscience, 2005 - Wiley Online Library
The perirhinal cortex of the temporal lobe has a crucial role in object recognition memory.
Cholinergic transmission within perirhinal cortex also seems to be important for this function …

The selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat

CKJ Lieben, A Blokland, A Şık, E Sung… - …, 2005 - nature.com
Abstract Antagonists at serotonin type 6 (5-HT 6) receptors show activity in models of
learning and memory. Although the underlying mechanism (s) are not well understood …

Memory enhancing and neuroprotective effects of selected ginsenosides

HY Bao, J Zhang, SJ Yeo, CS Myung, HM Kim… - Archives of Pharmacal …, 2005 - Springer
The effects of ginsenosides Rg 3 (R), Rg 3 (S) and Rg 5/Rk 1 (a mixture of Rg 5 and Rk 1, 1:
1, w/w), which are components isolated from processed Panax ginseng CA Meyer …

Pharmacological manipulation of cGMP and NO/cGMP in CNS drug discovery

MA Hollas, MB Aissa, SH Lee, JM Gordon-Blake… - Nitric Oxide, 2019 - Elsevier
The development of small molecule modulators of NO/cGMP signaling for use in the CNS
has lagged far behind the use of such clinical agents in the periphery, despite the central …

The role of nitric oxide in the object recognition memory

N Pitsikas - Behavioural brain research, 2015 - Elsevier
The novel object recognition task (NORT) assesses recognition memory in animals. It is a
non-rewarded paradigm that it is based on spontaneous exploratory behavior in rodents …