Liver-derived extracellular vesicles improve whole-body glycaemic control via inter-organ communication

PM Miotto, CH Yang, SN Keenan, W De Nardo… - Nature …, 2024 - nature.com
Small extracellular vesicles (EVs) are signalling messengers that regulate inter-tissue
communication through delivery of their molecular cargo. Here, we show that liver-derived …

Size-exclusion chromatography combined with DIA-MS enables deep proteome profiling of extracellular vesicles from melanoma plasma and serum

E Lattmann, L Räss, M Tognetti, JMM Gómez… - Cellular and Molecular …, 2024 - Springer
Extracellular vesicles (EVs) are important players in melanoma progression, but their use as
clinical biomarkers has been limited by the difficulty of profiling blood-derived EV proteins …

Extracellular vesicles: an emerging tool for wild immunology

C Espejo, VO Ezenwa - Discovery Immunology, 2024 - academic.oup.com
The immune system is crucial for defending organisms against pathogens and maintaining
health. Traditionally, research in immunology has relied on laboratory animals to understand …

Early cancer biomarker discovery using DIA-MS proteomic analysis of EVs from peripheral blood

C Espejo, B Lyons, GM Woods, R Wilson - Serum/plasma proteomics …, 2023 - Springer
One of the cornerstones of effective cancer treatment is early diagnosis. In this context, the
identification of proteins that can serve as cancer biomarkers in bodily fluids (“liquid …

Challenges of an emerging disease: the evolving approach to diagnosing devil facial tumour disease

C Espejo, AL Patchett, R Wilson, AB Lyons, GM Woods - Pathogens, 2021 - mdpi.com
Devil Facial Tumour Disease (DFTD) is an emerging infectious disease that provides an
excellent example of how diagnostic techniques improve as disease-specific knowledge is …

Development of synthetic immunological tools for Tasmanian devil research

AJ De Luca - 2022 - figshare.utas.edu.au
The Tasmanian devil (Sarcophilus harrisii) is the world ‚ÄövÑv¥ s largest extant carnivorous
marsupial. The wild population of devils has been decimated by two transmissible cancers …