[HTML][HTML] IGF system targeted therapy: Therapeutic opportunities for ovarian cancer

JAL Liefers-Visser, RAM Meijering, AKL Reyners… - Cancer Treatment …, 2017 - Elsevier
The insulin-like growth factor (IGF) system comprises multiple growth factor receptors,
including insulin-like growth factor 1 receptor (IGF-1R), insulin receptor (IR)-A and-B. These …

Tackling drug resistance in ovarian cancer with epigenetic targeted drugs

L Zhao, H Guo, X Chen, W Zhang, Q He, L Ding… - European Journal of …, 2022 - Elsevier
Epigenetic dysregulation plays a crucial role in the development and progression of ovarian
cancer. Since the first experiment conducted on resistant ovarian cancer cells using …

[HTML][HTML] Microtubule inhibitor, SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells

A Kulshrestha, GK Katara, SA Ibrahim, R Patil… - Oncotarget, 2017 - ncbi.nlm.nih.gov
In ovarian cancer (OVCA), treatment failure due to chemo-resistance is a serious challenge.
It is therefore critical to identify new therapies that are effective against resistant tumors and …

LAMP3 expression correlated with poor clinical outcome in human ovarian cancer

D Wang, X Cao, Y Zhang, Y Liu, C Yao, W Ge… - Tumor …, 2017 - journals.sagepub.com
Lysosome-associated membrane protein 3 belongs to the lysosome-associated membrane
glycoprotein family, which is associated with lymph node, metastasis, poor overall survival …

[HTML][HTML] VSV based virotherapy in ovarian cancer: the past, the present and… future?

BU Orzechowska, M Jędryka, K Zwolińska… - Journal of …, 2017 - ncbi.nlm.nih.gov
The standard approach to treating patients with advanced epithelial ovarian cancer (EOC)
after primary debulking surgery remains taxane and platinum-based chemotherapy. Despite …

Association between sarcopenia and survival in patients with gynecologic cancer: A systematic review and meta-analysis

WL Lin, THY Nguyen, CY Lin, LM Wu… - Frontiers in …, 2023 - frontiersin.org
Background Despite prior attempts to evaluate the effects of sarcopenia on survival among
patients with gynecologic cancer, the results of these studies have not been consistent. The …

Chemotherapy Toxicity in BRCA Mutation Carriers Undergoing First‐Line Platinum‐Based Chemotherapy

O Weitzner, Y Yagur, Y Kadan, ME Beiner… - The …, 2019 - academic.oup.com
Objective BRCA mutations are the most frequent mutations causing homologous
recombination defects in epithelial ovarian cancers (EOC). Germline mutation carriers are …

TNFAIP8 promotes cell growth by regulating the Hippo pathway in epithelial ovarian cancer

Y Xie, F Zhou, X Zhao - Experimental and therapeutic …, 2018 - spandidos-publications.com
Tumor necrosis factor‑α‑induced protein 8 (TNFAIP8) is an independent prognostic factor for
cancer‑specific and disease‑free survival in patients with epithelial ovarian cancer (EOC) …

Germline BRCA mutation carriers are more likely to undergo cytoreductive surgery for relapsed, platinum sensitive, ovarian cancer

K Yfat, K Mariam, B Mario, H Hal, J Dana, S Lina… - Gynecologic …, 2022 - Elsevier
Objective BRCA mutations have been associated with improved outcomes in ovarian cancer
patients. This study's objective was to compare the secondary cytoreduction surgery (SCS) …

[PDF][PDF] Identification of LINC01503 as Biomarker Regulated by CTBP1 with Prognostic and Diagnostic Role in Epithelial Ovarian Cancer

Y Wang, Z Wei, J Zhang, X Wang, X Li - 2021 - scholar.archive.org
Background: Epithelial ovarian cancer (EOC) is a disease with high morbidity and mortality
worldwide, which is seriously harmful to female health. LncRNA has an important …