The potential of oligonucleotide therapeutics is undeniable as more than 15 drugs have
been approved to treat various diseases in the liver, central nervous system (CNS), and …

Progress with fluorescent flippers, small-molecule probes to image membrane tension in
living systems, has been limited by the effort needed to synthesize the twisted push–pull …

The key results of research in the field of development of methods and approaches to the
production of cyclic acetals based on petrochemical products are reviewed. The use of 1, 3 …

Silyl ether is particularly attractive for application in drug development for its easy
preparation, non-toxicity and remarkable biocompatibility. Earlier studies relied on the use of …

Disulfide rebridging methods are emerging recently as new ways to specifically modify
antibody-based entities and produce future conjugates. Briefly, the solvent-accessible …

Protein modification is a powerful and important tool for the generation of bioconjugates of
immense diagnostic and therapeutic utility. Strategies towards achieving efficient, selective …

Bioconjugation is essential in many fields such as biotechnology, medical diagnostics, and
drug development. It refers to the process of attaching a synthetic molecule or biomolecule …

Bioorthogonal chemistry refers to a chemical reaction taking place within a living system,
without interfering with any native, biochemical processes. Over the last 20 years, research …