Purpose: The aim of this review is to (1) retrieve all data validating the Session-rating of
perceived exertion (RPE)-method using various criteria,(2) highlight the rationale of this …

During exercise, there is a progressive reduction in the ability to produce muscle forces.
Processes within the nervous system, as well as within the muscles contribute to this fatigue …

The nature of the transition from acute to chronic pain still eludes explanation, but chronic
pain resulting from surgery provides a natural experiment that invites clinical …

Fatigue is one of the most common debilitating symptoms reported by persons with multiple
sclerosis (MS). It reflects feelings of tiredness, lack of energy, low motivation, and difficulty in …

Perception of effort, also known as perceived exertion or sense of effort, can be described as
a cognitive feeling of work associated with voluntary actions. The aim of the present review …

Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise
classification. It is often considered as part of the global overview of functional somatic …

Neuromuscular fatigue compromises exercise performance and is determined by central
and peripheral mechanisms. Interactions between the two components of fatigue can occur …

Autonomic nervous system adjustments to the heart and blood vessels are necessary for
mediating the cardiovascular responses required to meet the metabolic demands of working …

Group III and IV muscle afferents originating in exercising limb muscle play a significant role
in the development of fatigue during exercise in humans. Feedback from these sensory …

Statins are effective drugs to reduce cardiovascular events secondary to dyslipidemia;
however, they cause frequent undesirable side effects. The incidence of statin-induced …