Numerical fluid–structure interaction (FSI) methods have been widely used to predict the
cardiac mechanics and associated hemodynamics of native and artificial heart valves …

Even though the mechanical heart valve (MHV) has been used routinely in clinical practice
for over 60 years, the occurrence of serious complications such as blood clotting remains to …

A model for platelet activation based on the theory of damage, incorporating cumulative
effects of stress history and past damage (senescence) was applied to a three‐dimensional …

We present comprehensive particle image velocimetry measurements and direct numerical
simulation (DNS) of physiological, pulsatile flow through a clinical quality bileaflet …

The main purpose of this study is to reproduce in silico the dynamics of a bileaflet
mechanical heart valve (MHV; St Jude Hemodynamic Plus, 27mm characteristic size) by …

Patients who receive prosthetic heart valve (PHV) implants require mandatory
anticoagulation medication after implantation due to the thrombogenic potential of the valve …

We have performed high-resolution fluid–structure interaction simulations of physiologic
pulsatile flow through a bi-leaflet mechanical heart valve (BMHV) in an anatomically realistic …

Purpose The physiological flow dynamics within the Valsalva sinuses, in terms of global and
local parameters, are still not fully understood. This study attempts to identify the …

We develop an overset-curvilinear immersed boundary (overset-CURVIB) method in a
general non-inertial frame of reference to simulate a wide range of challenging biological …

Thromboembolism and the attendant risk of cardioembolic stroke remains an impediment to
the development of prosthetic cardiovascular devices. In particular, altered haemodynamics …