Background: An emerging paradigm supports the notion that deregulation of fatty acid
synthase (FASN)-catalyzed de novo FA biogenesis could play a central role in the …

Abstract Treatment with second generation antipsychotics (SGAs), notably olanzapine and
clozapine, causes severe obesity side effects. Antagonism of histamine H1 receptors has …

Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease and is characterized by excessive hepatic lipid accumulation. Many studies have …

Transcription factor Nrf2 (NF-E2 p45-related factor 2) regulates the cellular redox
homoeostasis and cytoprotective responses, allowing adaptation and survival under …

Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases with
limited treatment options. Moreover, its prevalence is doubled in type 2 diabetes mellitus …

In vivo incorporation of isotopically labeled unnatural amino acids into large proteins
drastically reduces the complexity of nuclear magnetic resonance (NMR) spectra …

It is known that a high‐cholesterol diet induces oxidative stress, inflammatory response, and
beta‐amyloid (Aβ) accumulation in mouse brain, resulting in neurodegenerative changes …

Fatty acid (FA) biosynthesis plays a central role in the metabolism of living cells as building
blocks of biological membranes, energy reserves of the cell, and precursors to second …

Fatty acid synthases (FASs) are central to metabolism but are also of biotechnological
interest for the production of fine chemicals and biofuels from renewable resources. During …

Prostate cancer (PCa) cells exploit cellular metabolic reprogramming as their survival
advantage, especially aberrant lipid signaling and metabolism. Although recent studies …