Mechanical forces associated with blood flow play important roles in the acute control of
vascular tone, the regulation of arterial structure and remodeling, and the localization of …

Biofilm and granular sludge processes are promising biotechnology for wastewater
treatment. The formation, structure and metabolism of immobilized microbial community are …

CLINICAL BLEEDING or thrombosis results from a disturbance in the balance between a
complex network of procoagulant and anticoagulant factors. This network involves three …

An important issue in tissue engineering concerns the possibility of limited tissue ingrowth in
tissue-engineered constructs because of insufficient nutrient transport. We report a dynamic …

Atherosclerotic lesions tend to localize at curvatures and branches of the arterial system,
where the local flow is often disturbed and irregular (eg, flow separation, recirculation …

The classic paradigm for in vitro tissue engineering of bone involves the isolation and
culture of donor osteoblasts or osteoprogenitor cells within three‐dimensional (3D) scaffold …

The endothelium lining human arteries is a continuum of endothelial cells. The flowing blood
imposes a shear stress on the endothelium. To compute the internal stress in the …

The viscoelastic properties of cultured endothelial cells exposed to shear stress were
measured by the micropipette technique and analyzed using a standard linear viscoelastic …

The rapid developments in biotechnology have resulted in the identification and use of a
large variety of biologically active substances produced from microbial, plant and animal …

A microfluidic device was fabricated via photolithographic techniques which can create
transient elongational and shear forces ranging over three orders of magnitude while still …