Functions of the neocortex depend on its bidirectional communication with the thalamus, via cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …
Epileptic seizures represent dysfunctional neural networks dominated by excessive and/or hypersynchronous activity. Recent progress in the field has outlined two concepts regarding …
EM Izhikevich, GM Edelman - Proceedings of the national …, 2008 - National Acad Sciences
The understanding of the structural and dynamic complexity of mammalian brains is greatly facilitated by computer simulations. We present here a detailed large-scale thalamocortical …
Certain neurons in the mammalian brain have long been known to be joined by gap junctions, which are the most common type of electrical synapse. More recently, cloning of …
FC Crick, C Koch - … Transactions of the Royal Society B …, 2005 - royalsocietypublishing.org
The claustrum is a thin, irregular, sheet-like neuronal structure hidden beneath the inner surface of the neocortex in the general region of the insula. Its function is enigmatic. Its …
D Pinault - Brain research reviews, 2004 - Elsevier
On the basis of theoretical, anatomical, psychological and physiological considerations, Francis Crick (1984) proposed that, during selective attention, the thalamic reticular nucleus …
BW Connors, MA Long - Annu. Rev. Neurosci., 2004 - annualreviews.org
▪ Abstract Many neurons in the mammalian central nervous system communicate through electrical synapses, defined here as gap junction–mediated connections. Electrical …
Corticothalamic neurons provide massive input to the thalamus. This top-down projection may allow the cortex to regulate sensory processing by modulating the excitability of …
R Bruzzone, SG Hormuzdi, MT Barbe… - Proceedings of the …, 2003 - National Acad Sciences
Database search has led to the identification of a family of proteins, the pannexins, which share some structural features with the gap junction forming proteins of invertebrates and …