Design challenges in polymeric scaffolds for tissue engineering

MI Echeverria Molina, KG Malollari… - … in Bioengineering and …, 2021 - frontiersin.org
Numerous surgical procedures are daily performed worldwide to replace and repair
damaged tissue. Tissue engineering is the field devoted to the regeneration of damaged …

Recent advances in droplet microfluidics

Y Ding, PD Howes, AJ deMello - Analytical chemistry, 2019 - ACS Publications
Prominent within this technology set are droplet-based microfluidic systems, 3 in which
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …

Advances in porous scaffold design for bone and cartilage tissue engineering and regeneration

A Cheng, Z Schwartz, A Kahn, X Li, Z Shao… - … Engineering Part B …, 2019 - liebertpub.com
Tissue engineering of bone and cartilage has progressed from simple to sophisticated
materials with defined porosity, surface features, and the ability to deliver biological factors …

Synthetic scaffolds for musculoskeletal tissue engineering: cellular responses to fiber parameters

TL Jenkins, D Little - NPJ Regenerative medicine, 2019 - nature.com
Tissue engineering often uses synthetic scaffolds to direct cell responses during engineered
tissue development. Since cells reside within specific niches of the extracellular matrix, it is …

Collagen scaffolds in cartilage tissue engineering and relevant approaches for future development

V Irawan, TC Sung, A Higuchi, T Ikoma - Tissue engineering and …, 2018 - Springer
Background: Cartilage tissue engineering (CTE) aims to obtain a structure mimicking native
cartilage tissue through the combination of relevant cells, three-dimensional scaffolds, and …

Protein-reactive nanofibrils decorated with cartilage-derived decellularized extracellular matrix for osteochondral defects

HS Kim, N Mandakhbayar, HW Kim, KW Leong… - Biomaterials, 2021 - Elsevier
Cartilage defect is difficult to heal due to its avascular properties. Implantation of
mesenchymal stem cell is one of the most promising approach for regenerating cartilage …

Maneuvering the migration and differentiation of stem cells with electrospun nanofibers

J Xue, D Pisignano, Y Xia - Advanced Science, 2020 - Wiley Online Library
Electrospun nanofibers have been extensively explored as a class of scaffolding materials
for tissue regeneration, because of their unique capability to mimic some features and …

The effect of physical cues of biomaterial scaffolds on stem cell behavior

S Wang, S Hashemi, S Stratton… - Advanced Healthcare …, 2021 - Wiley Online Library
Stem cells have been sought as a promising cell source in the tissue engineering field due
to their proliferative capacity as well as differentiation potential. Biomaterials have been …

Surface engineering of cardiovascular devices for improved hemocompatibility and rapid endothelialization

J Zhao, Y Feng - Advanced Healthcare Materials, 2020 - Wiley Online Library
Cardiovascular devices have been widely applied in the clinical treatment of cardiovascular
diseases. However, poor hemocompatibility and slow endothelialization on their surface still …

Harnessing fiber diameter-dependent effects of myoblasts toward biomimetic scaffold-based skeletal muscle regeneration

N Narayanan, C Jiang, C Wang, G Uzunalli… - … in Bioengineering and …, 2020 - frontiersin.org
Regeneration of skeletal muscles is limited in cases of volumetric muscle loss and muscle
degenerative diseases. Therefore, there is a critical need for developing strategies that …