Peptide nucleic acid (PNA) stands as one of the most successful artificial oligonucleotide
mimetics. Salient features include the stability of hybridization complexes (either as …

Light-powered catalysis has found broad utility as a chemical transformation strategy, with
widespread impact on energy, environment, drug discovery and human health. A noteworthy …

The importance of transition metal catalysis is exemplified by its wide range of applications,
for example in the synthesis of chemicals, natural products, and pharmaceuticals. However …

Combining synthetic chemistry and biocatalysis is a promising but underexplored approach
to intracellular catalysis. We report a strategy to codeliver a single-chain nanoparticle …

Complementing enzymes in their native environment with either homogeneous or
heterogeneous catalysts is challenging due to the sea of functionalities present within a cell …

Chemical modification of nucleic acids in living cells can be sterically hindered by tight
packing of bioorthogonal functional groups in chromatin. To address this limitation, we report …

Bioorthogonal chemistry largely relies on the use of abiotic metals to catalyze new-to-nature
reactions in living systems. Over the past decade, metal complexes and metal-encapsulated …

The site-specific delivery of antitumor agents is a rapidly developing field that relies on
prodrug activation and uncaging strategies. For this purpose, a wide range of homogeneous …

Visible Light Photoredox Catalysis Using Ruthenium Complexes in Chemical Biology - Angerani -
2019 - Chemistry – A European Journal - Wiley Online Library Skip to Article Content Skip to Article …

Bioorthogonal reactions that proceed readily under physiological conditions without
interference from biomolecules have found widespread application in the life sciences …