Ethnobotany, Biological Activities and Phytochemical Compounds of Some Species of the Genus Eryngium (Apiaceae), from the Central-Western Region of Mexico
JG Cárdenas-Valdovinos, I García-Ruiz… - Molecules, 2023 - mdpi.com
There are approximately 250 species of Eryngium L. distributed throughout the world, with
North America and South America being centers of diversity on this continent. In the central …
North America and South America being centers of diversity on this continent. In the central …
Advanced bioinformatics tools in the pharmacokinetic profiles of natural and synthetic compounds with anti-diabetic activity
AM Udrea, G Gradisteanu Pircalabioru, AA Boboc… - Biomolecules, 2021 - mdpi.com
Diabetes represents a major health problem, involving a severe imbalance of blood sugar
levels, which can disturb the nerves, eyes, kidneys, and other organs. Diabes management …
levels, which can disturb the nerves, eyes, kidneys, and other organs. Diabes management …
[HTML][HTML] Design, synthesis and bioevaluation of new vanillin hybrid as multitarget inhibitor of α-glucosidase, α-amylase, PTP-1B and DPP4 for the treatment of type-II …
MA Huneif, DB Alshehri, KS Alshaibari… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a real challenge to the recent era and is one of the major diseases
for initiating life-threatening disorders. In current research, a compound was designed by …
for initiating life-threatening disorders. In current research, a compound was designed by …
Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic …
In the current study, a series of new (2 S, 3 S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …
Chemical and Nutritional Profiling of the Seaweed Dictyota dichotoma and Evaluation of Its Antioxidant, Antimicrobial and Hypoglycemic Potentials
Seaweed has been known to possess beneficial effects forhuman health due to the
presence of functional bioactive components. The n-butanol and ethyl acetate extracts of …
presence of functional bioactive components. The n-butanol and ethyl acetate extracts of …
In-vitro, in-vivo, molecular docking and ADMET studies of 2-substituted 3, 7-dihydroxy-4H-chromen-4-one for oxidative stress, inflammation and Alzheimer's disease
Plants' bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich
dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated …
dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated …
Synthesis, molecular docking and enzyme inhibitory approaches of some new chalcones engrafted pyrazole as potential antialzheimer, antidiabetic and antioxidant …
MS Islam, AM Al-Majid, EN Sholkamy, S Yousuf… - Journal of Molecular …, 2022 - Elsevier
About 25 chalcones engrafted pyrazole scaffold combined with benzothiophene and indole
moieties 5a-y were designed and constructed in two steps using readily available acetyl …
moieties 5a-y were designed and constructed in two steps using readily available acetyl …
α-glucosidase, α-amylase and antioxidant evaluations of isolated bioactives from wild strawberry
MA Huneif, SM Alqahtani, A Abdulwahab… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a metabolic disorder and is a global challenge to the current medicinal
chemists and pharmacologists. This research has been designed to isolate and evaluate …
chemists and pharmacologists. This research has been designed to isolate and evaluate …
3-(((1S,3S)-3-((R)-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target …
The chiral drug candidates have more effective binding affinities for their specific protein or
receptor site for the onset of pharmacological action. Achieving all carbon stereopure …
receptor site for the onset of pharmacological action. Achieving all carbon stereopure …
New succinimide–thiazolidinedione hybrids as multitarget antidiabetic agents: design, synthesis, bioevaluation, and molecular modelling studies
Diabetes mellitus (DM) is a metabolic disorder majorly arising from the pathophysiology of
the pancreas manifested as a decline in the insulin production or the tissue's resistance to …
the pancreas manifested as a decline in the insulin production or the tissue's resistance to …