[HTML][HTML] Under control: The innate immunity of fish from the inhibitors' perspective

A Rebl, T Goldammer - Fish & shellfish immunology, 2018 - Elsevier
The innate immune response involves a concerted network of induced gene products,
preformed immune effectors, biochemical signalling cascades and specialised cells …

An overview of complement systems in teleosts

M Li, H Zhang - Developmental & Comparative Immunology, 2022 - Elsevier
Complement plays an important role in the innate immune system, and it comprises about
35 individual proteins. In mammals, complement is activated via three different pathways …

Hematological varieties, histological changes, and immune responses in the early stage of infection with Vibrio parahaemolyticus in Black rockfish Sebastes schlegelii

Y Gao, G Han, L Qiang, L Zhang, R Tan, Y Yu - Aquaculture International, 2023 - Springer
Black rockfish (Sebastes schlegelii) is a marine fish with high financial value; however, the
frequent occurrence of bacterial diseases has caused a production decline and economic …

Molecular characterization and comparative expression analysis of two teleostean pro-inflammatory cytokines, IL-1β and IL-8, from Sebastes schlegeli

H Herath, DAS Elvitigala, GI Godahewa, N Umasuthan… - Gene, 2016 - Elsevier
Abstract Interleukin 1β (IL-1β) and interleukin 8 (IL-8) are two major pro-inflammatory
cytokines which play a central role in initiation of inflammatory responses against bacterial …

Identification and characterization of C1 inhibitor in Nile tilapia (Oreochromis niloticus) in response to pathogenic bacteria

M Ding, M Chen, X Zhong, Y Wang, S Fu, X Yin… - Fish & shellfish …, 2017 - Elsevier
Abstract C1 inhibitor (C1INH) is a multi-functional serine protease inhibitor in plasmatic
cascades, not only inactivating various proteases, but also regulating both complement and …

Gene structure, molecular characterization and transcriptional expression of two p38 isoforms (MAPK11 and MAPK14) from rock bream (Oplegnathus fasciatus)

N Umasuthan, S Bathige, JK Noh, J Lee - Fish & shellfish immunology, 2015 - Elsevier
The p38 kinases are one of the four subgroups of mitogen-activated protein kinase (MAPK)
superfamily which are involved in the innate immunity. The p38 subfamily that includes four …

The role of serpin protein on the natural immune defense against pathogen infection in Lampetra japonica

D Wang, M Gou, J Hou, Y Pang, Q Li - Fish & Shellfish Immunology, 2019 - Elsevier
Serine protease inhibitors (serpins) are a large protein family that is involved in various
physiological processes and is known to regulate innate immunity pathways. However …

C1r and C1s from Nile tilapia (Oreochromis niloticus): Molecular characterization, transcriptional profiling upon bacterial and IFN-γ inductions and potential role in …

X Zhong, M Chen, M Ding, M Zhong, B Li… - Fish & shellfish …, 2017 - Elsevier
The complement components C1r and C1s play a vital role in immunity with the activation of
C1 complex in the classical complement pathway against pathogen infection. In this study …

Molecular, genomic, and expressional delineation of a piscidin from rock bream (Oplegnathus fasciatus) with evidence for the potent antimicrobial activities of Of-Pis1 …

N Umasuthan, MS Mothishri, WS Thulasitha… - Fish & Shellfish …, 2016 - Elsevier
The piscidin family comprises a group of antimicrobial peptides (AMPs) that are vital
components of teleost innate immunity. Piscidins protect the host from pathogens, through …

Identification of a gene encoding a membrane-anchored toll-like receptor 5 (TLR5M) in Oplegnathus fasciatus that responds to flagellin challenge and activates NF-κB

N Umasuthan, S Bathige, WS Thulasitha… - Fish & shellfish …, 2017 - Elsevier
Abstract Toll-like receptor 5 (TLR5) recognizes bacterial flagellin and induces the
downstream signaling through the myeloid differentiation primary response gene 88 …