Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Cyanobacteria and cyanotoxins in a changing environment: Concepts, controversies, challenges

I Chorus, J Fastner, M Welker - Water, 2021 - mdpi.com
Concern is widely being published that the occurrence of toxic cyanobacteria is increasing
in consequence of climate change and eutrophication, substantially threatening human …

The Natural Products Atlas 2.0: a database of microbially-derived natural products

JA van Santen, EF Poynton, D Iskakova… - Nucleic acids …, 2022 - academic.oup.com
Within the natural products field there is an increasing emphasis on the study of compounds
from microbial sources. This has been fuelled by interest in the central role that …

The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry

H Mohammed Taha, R Aalizadeh, N Alygizakis… - Environmental Sciences …, 2022 - Springer
Abstract Background The NORMAN Association (https://www. norman-network. com/)
initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www. norman …

As we drink and breathe: Adverse health effects of microcystins and other harmful algal bloom toxins in the liver, gut, lungs and beyond

A Lad, JD Breidenbach, RC Su, J Murray, R Kuang… - Life, 2022 - mdpi.com
Freshwater harmful algal blooms (HABs) are increasing in number and severity worldwide.
These HABs are chiefly composed of one or more species of cyanobacteria, also known as …

A review of common cyanotoxins and their effects on fish

H Falfushynska, N Kasianchuk, E Siemens, E Henao… - Toxics, 2023 - mdpi.com
Global warming and human-induced eutrophication drive the occurrence of various
cyanotoxins in aquatic environments. These metabolites reveal diversified mechanisms of …

Biodegradation of MC-LR and its key bioactive moiety Adda by Sphingopyxis sp. YF1: Comprehensive elucidation of the mechanisms and pathways

J Wei, Z Pengji, J Zhang, T Peng, J Luo, F Yang - Water Research, 2023 - Elsevier
Microcystins (MCs) are harmful to the ecology and public health. Some bacteria can
degrade MCs into Adda, but few can destroy Adda. Adda is the key bioactive moiety of MCs …

The essentials of marine biotechnology

A Rotter, M Barbier, F Bertoni, AM Bones… - Frontiers In marine …, 2021 - frontiersin.org
Coastal countries have traditionally relied on the existing marine resources (eg, fishing,
food, transport, recreation, and tourism) as well as tried to support new economic endeavors …

Identification of Novel Microcystins Using High-Resolution MS and MSn with Python Code

D Baliu-Rodriguez, NJ Peraino… - Environmental …, 2022 - ACS Publications
Cyanotoxins called microcystins (MCs) are highly toxic and can be present in drinking water
sources. Determining the structure of MCs is paramount because of its effect on toxicity …

Cyanobacteria: a natural source for controlling agricultural plant diseases caused by fungi and oomycetes and improving plant growth

H Righini, O Francioso, A Martel Quintana, R Roberti - Horticulturae, 2022 - mdpi.com
Cyanobacteria, also called blue-green algae, are a group of prokaryotic microorganisms
largely distributed in both terrestrial and aquatic environments. They produce a wide range …