Lipid droplets and lipid mediators in viral infection and immunity

EA Monson, AM Trenerry, JL Laws… - FEMS microbiology …, 2021 - academic.oup.com
Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …

Mosquito innate immunity

A Kumar, P Srivastava, P Sirisena, SK Dubey, R Kumar… - Insects, 2018 - mdpi.com
Mosquitoes live under the endless threat of infections from different kinds of pathogens such
as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical …

Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection

WS Lee, JA Webster, ET Madzokere, EB Stephenson… - Parasites & vectors, 2019 - Springer
Mosquito-borne diseases are associated with major global health burdens. Aedes spp. and
Culex spp. are primarily responsible for the transmission of the most medically important …

Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response

EA Monson, KM Crosse, M Duan, W Chen… - Nature …, 2021 - nature.com
Lipid droplets (LDs) are increasingly recognized as critical organelles in signalling events,
transient protein sequestration and inter-organelle interactions. However, the role LDs play …

Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses

MA Martín-Acebes, Á Vázquez-Calvo, JC Saiz - Progress in lipid research, 2016 - Elsevier
Flaviviruses are emerging arthropod-borne pathogens that cause life-threatening diseases
such as yellow fever, dengue, West Nile encephalitis, tick-borne encephalitis, Kyasanur …

Production, transmission, pathogenesis, and control of dengue virus: a literature‐based undivided perspective

MT Islam, C Quispe, J Herrera-Bravo… - BioMed Research …, 2021 - Wiley Online Library
Dengue remains one of the most serious and widespread mosquito‐borne viral infections in
human beings, with serious health problems or even death. About 50 to 100 million people …

Lipid hijacking: a unifying theme in vector-borne diseases

AJ O'Neal, LR Butler, A Rolandelli, SD Gilk, JHF Pedra - Elife, 2020 - elifesciences.org
Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Lipid droplets and the host–pathogen dynamic: FATal attraction?

M Bosch, MJ Sweet, RG Parton, A Pol - Journal of Cell Biology, 2021 - rupress.org
In the ongoing conflict between eukaryotic cells and pathogens, lipid droplets (LDs) emerge
as a choke point in the battle for nutrients. While many pathogens seek the lipids stored in …

Mammalian lipid droplets: Structural, pathological, immunological and anti-toxicological roles

N Hammoudeh, C Soukkarieh, DJ Murphy… - Progress in lipid …, 2023 - Elsevier
Mammalian lipid droplets (LDs) are specialized cytosolic organelles consisting of a neutral
lipid core surrounded by a membrane made up of a phospholipid monolayer and a specific …

Lipid metabolism in insect disease vectors

KC Gondim, GC Atella, EG Pontes… - Insect biochemistry and …, 2018 - Elsevier
More than a third of the world population is at constant risk of contracting some insect-
transmitted disease, such as Dengue fever, Zika virus disease, malaria, Chagas' disease …