Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

Clinical applications of chemical exchange saturation transfer (CEST) MRI

KM Jones, AC Pollard, MD Pagel - Journal of Magnetic …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
been developed and employed in multiple clinical imaging research centers worldwide …

Furin-mediated intracellular self-assembly of olsalazine nanoparticles for enhanced magnetic resonance imaging and tumour therapy

Y Yuan, J Zhang, X Qi, S Li, G Liu, S Siddhanta… - Nature materials, 2019 - nature.com
Among the strategies used for enhancement of tumour retention of imaging agents or
anticancer drugs is the rational design of probes that undergo a tumour-specific enzymatic …

Rapid and quantitative chemical exchange saturation transfer (CEST) imaging with magnetic resonance fingerprinting (MRF)

O Cohen, S Huang, MT McMahon… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To develop a fast magnetic resonance fingerprinting (MRF) method for quantitative
chemical exchange saturation transfer (CEST) imaging. Methods We implemented a CEST …

One-component supramolecular filament hydrogels as theranostic label-free magnetic resonance imaging agents

LL Lock, Y Li, X Mao, H Chen, V Staedtke, R Bai… - ACS …, 2017 - ACS Publications
Gadolinium (Gd)-based compounds and materials are the most commonly used magnetic
resonance imaging (MRI) contrast agents in the clinic; however, safety concerns associated …

Assessments of tumor metabolism with CEST MRI

JM Goldenberg, MD Pagel - NMR in Biomedicine, 2019 - Wiley Online Library
Chemical exchange saturation transfer (CEST) is a relatively new contrast mechanism for
MRI. CEST MRI exploits a specific MR frequency (chemical shift) of a molecule while …

Construction of nanomaterials as contrast agents or probes for glioma imaging

W Zhao, X Yu, S Peng, Y Luo, J Li, L Lu - Journal of Nanobiotechnology, 2021 - Springer
Malignant glioma remains incurable largely due to the aggressive and infiltrative nature, as
well as the existence of blood–brain-barrier (BBB). Precise diagnosis of glioma, which aims …

[HTML][HTML] Label-free CEST MRI detection of citicoline-liposome drug delivery in ischemic stroke

H Liu, A Jablonska, Y Li, S Cao, D Liu, H Chen… - Theranostics, 2016 - ncbi.nlm.nih.gov
Citicoline (CDPC) is a natural supplement with well-documented neuroprotective effects in
the treatment of neurodegenerative diseases. In the present study, we sought to exploit …

QUESP and QUEST revisited–fast and accurate quantitative CEST experiments

M Zaiss, G Angelovski, E Demetriou… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose Chemical exchange saturation transfer (CEST) NMR or MRI experiments allow
detection of low concentrated molecules with enhanced sensitivity via their proton exchange …

Imaging of sugar‐based contrast agents using their hydroxyl proton exchange properties

L Knutsson, X Xu, PCM van Zijl… - NMR in …, 2023 - Wiley Online Library
The ability of CEST MRI to detect the presence of millimolar concentrations of non‐metallic
contrast agents has made it possible to study, non‐invasively, important biological …