Synaptic plasticity forms and functions

JC Magee, C Grienberger - Annual review of neuroscience, 2020 - annualreviews.org
Synaptic plasticity, the activity-dependent change in neuronal connection strength, has long
been considered an important component of learning and memory. Computational and …

Diversity and dynamism in the cerebellum

CI De Zeeuw, SG Lisberger, JL Raymond - Nature neuroscience, 2021 - nature.com
The past several years have brought revelations and paradigm shifts in research on the
cerebellum. Historically viewed as a simple sensorimotor controller with homogeneous …

Activity map of a cortico-cerebellar loop underlying motor planning

J Zhu, H Hasanbegović, LD Liu, Z Gao, N Li - Nature neuroscience, 2023 - nature.com
The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown
how the two structures organize into functional networks to mediate specific behaviors. Here …

The cerebellum: adaptive prediction for movement and cognition

AA Sokolov, RC Miall, RB Ivry - Trends in cognitive sciences, 2017 - cell.com
Over the past 30 years, cumulative evidence has indicated that cerebellar function extends
beyond sensorimotor control. This view has emerged from studies of neuroanatomy …

Reward signals in the cerebellum: origins, targets, and functional implications

D Kostadinov, M Häusser - Neuron, 2022 - cell.com
The cerebellum has long been proposed to play a role in cognitive function, although this
has remained controversial. This idea has received renewed support with the recent …

Re-evaluating circuit mechanisms underlying pattern separation

NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlapping patterns of activity that represent sensory and motor information. Pattern …

Computational principles of supervised learning in the cerebellum

JL Raymond, JF Medina - Annual review of neuroscience, 2018 - annualreviews.org
Supervised learning plays a key role in the operation of many biological and artificial neural
networks. Analysis of the computations underlying supervised learning is facilitated by the …

Bidirectional learning in upbound and downbound microzones of the cerebellum

CI De Zeeuw - Nature Reviews Neuroscience, 2021 - nature.com
Over the past several decades, theories about cerebellar learning have evolved. A relatively
simple view that highlighted the contribution of one major form of heterosynaptic plasticity to …

The cerebellar cortex

C Hull, WG Regehr - Annual review of neuroscience, 2022 - annualreviews.org
The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Prediction signals in the cerebellum: beyond supervised motor learning

C Hull - elife, 2020 - elifesciences.org
While classical views of cerebellar learning have suggested that this structure predominantly
operates according to an error-based supervised learning rule to refine movements …