Rejuvenation of aged oocyte through exposure to young follicular microenvironment
Reproductive aging is a major cause of fertility decline, attributed to decreased oocyte
quantity and developmental potential. A possible cause is aging of the surrounding follicular …
quantity and developmental potential. A possible cause is aging of the surrounding follicular …
Fbxo28 is essential for spindle migration and morphology during mouse oocyte meiosis I
H Chang, C Huang, S Cheng, J Li, X Wang - International Journal of …, 2024 - Elsevier
Spindle migration and assembly regulates asymmetric oocyte division, which is essential for
fertility. Fbxo28, as a member of SCF (Skp1-Cul1-F-box) ubiquitin E3 ligases complex, is …
fertility. Fbxo28, as a member of SCF (Skp1-Cul1-F-box) ubiquitin E3 ligases complex, is …
Integrating clinical and genomic landscape analysis of perineural invasion identify ACTA1 as an oncogene for oral squamous cell carcinoma
S Chen, T Zhao, Y Song, X Huang, Y Ni… - Frontiers in Cell and …, 2024 - frontiersin.org
Background Perineural invasion (PNI) has been shown to be a key pathological feature of
several types of cancer, including oral squamous epithelial carcinoma (OSCC). However …
several types of cancer, including oral squamous epithelial carcinoma (OSCC). However …
The formins inhibitor SMIFH2 inhibits the cytoskeleton dynamics and mitochondrial function during goat oocyte maturation
MH Pan, R Xu, Z Zheng, J Xiong, H Dong, Q Wei, B Ma - Theriogenology, 2023 - Elsevier
The cytoskeleton plays a crucial role in facilitating the successful completion of the meiotic
maturation of oocytes. Its influence extends to the process of oocyte nuclear maturation and …
maturation of oocytes. Its influence extends to the process of oocyte nuclear maturation and …
Arf6 GTPase deficiency leads to porcine oocyte quality decline during aging
KH Zhang, L Jiao, Y Wang, SC Sun - The FASEB Journal, 2024 - Wiley Online Library
Arf6 is a member of ADP‐ribosylation factor (Arf) family, which is widely implicated in the
regulation of multiple physiological processes including endocytic recycling, cytoskeletal …
regulation of multiple physiological processes including endocytic recycling, cytoskeletal …
Mechanistic Insights into FNBP4-Mediated Regulation of non-diaphanous formin FMN1 in Actin Cytoskeleton Dynamics
ABSTRACT Formin1 (FMN1), a member of the non-diaphanous formin family, is essential for
development and neuronal function. Unlike diaphanous-related formins, FMN1 is not subject …
development and neuronal function. Unlike diaphanous-related formins, FMN1 is not subject …