The challenges in the diagnosis, prognosis, and monitoring of Gaucher disease (GD), an
autosomal recessive inborn error of glycosphingolipid metabolism, can negatively impact …

Ferritin is a ubiquitous protein that is present in most tissues as a cytosolic protein. The
major and common role of ferritin is to bind Fe2+, oxidize it and sequester it in a safe form in …

Gaucher disease (GD) is caused by glucocerebrosidase deficiency leading to the
accumulation of sphingolipids in macrophages named “Gaucher's Cells”. These cells are …

Abstract Hydrogen peroxide (H 2 O 2) is an oxidant produced endogenously by several
enzymatic pathways. While it can cause molecular damage, H 2 O 2 also plays a role in …

Gaucher disease (GD) is a genetic disease with mutations in the GBA gene that encodes
glucocerebrosidase causing complications such as anaemia and bone disease. GD is …

A personalized treatment decision for Gaucher disease (GD) patients should be based on
relevant markers that are specific to GD, play a direct role in GD pathophysiology, exhibit low …

Gaucher disease (GD) is a recessively inherited lysosomal storage disorder in which
sphingolipids accumulates in the macrophages that transform into Gaucher cells. A growing …

Résumé Introduction La maladie de Gaucher (MG) est une maladie génétique lysosomale,
due à un déficit d'activité de la bêta-glucocérébrosidase, caractérisée par des atteintes …