Targeting Sterol O-Acyltransferase/Acyl-CoA:Cholesterol Acyltransferase (ACAT): A Perspective on Small-Molecule Inhibitors and Their Therapeutic Potential
P Bhattacharjee, N Rutland, MR Iyer - Journal of Medicinal …, 2022 - ACS Publications
Sterol O-acyltransferase (SOAT) is a membrane-bound enzyme that aids the esterification of
cholesterol and fatty acids to cholesterol esters. SOAT has been studied extensively as a …
cholesterol and fatty acids to cholesterol esters. SOAT has been studied extensively as a …
Cyclohexane-1, 3-dione derivatives as future therapeutic agents for NSCLC: QSAR modeling, in silico ADME-Tox properties, and structure-based drug designing …
The abnormal expression of the c-Met tyrosine kinase has been linked to the proliferation of
several human cancer cell lines, including non-small-cell lung cancer (NSCLC). In this …
several human cancer cell lines, including non-small-cell lung cancer (NSCLC). In this …
Flavonoids as P-glycoprotein inhibitors for multidrug resistance in cancer: an in-silico approach
Cancer has become a leading cause of mortality due to non-communicable diseases after
cardiovascular disease worldwide and is increasing day by day at a daunting pace …
cardiovascular disease worldwide and is increasing day by day at a daunting pace …