Since phosphorus is a component of hydroxyapatite, its prolonged deprivation affects bone
mineralization. Fibroblast growth factor 23 (FGF23) is essential for maintaining phosphate …

Dental mesenchymal stem cells (DMSCs) are multipotent progenitor cells that can
differentiate into multiple lineages including odontoblasts, osteoblasts, chondrocytes, neural …

The eggshell cuticle layer (ECL) and eggshell mineralized layer (EML) contain amounts of
glycoproteins and proteoglycans. However, there were few comprehensive reports about the …

Background The family with sequence similarity 20-member C (FAM20C) kinase, a Golgi
casein kinase, which is responsible for phosphorylating the majority of the extracellular …

The extracellular matrix (ECM) is central to the physiology of animal tissues, through its
multifaceted roles in tissue structure, mechanical properties, and cell interactions, and by its …

Fam20C, a typical member of Fam20 family, has been well-known as a Golgi casein kinase,
which is closely associated with Raine Syndrome (RS). It can phosphorylate many secreted …

Background Lung squamous cell carcinoma (LUSC) ranks among the carcinomas with the
highest incidence and dismal survival rates, suffering from a lack of effective therapeutic …

Raine syndrome (RNS) is a rare autosomal recessive osteosclerotic dysplasia. RNS is
caused by loss-of-function disease-causative variants of the FAM20C gene that encodes a …

Gliomas are the most prevalent and aggressive malignancies of the nervous system.
Previous bioinformatic studies have revealed the crucial role of the secretory pathway …

Myelodysplastic neoplasms (MDS) are hematopoietic stem cell disorders characterized by
ineffective hematopoiesis and dysplastic cells in the bone marrow (BM)[1]. In addition …