The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

The positive-negative axis of emotional valence has long been recognized as fundamental
to adaptive behavior, but its origin and underlying function have largely eluded formal …

Over the past decade, there has been a surge of empirical research investigating mental
disorders as complex systems. In this article, we investigate how to best make use of this …

Over the last decades, theoretical perspectives in the interdisciplinary field of the affective
sciences have proliferated rather than converged due to differing assumptions about what …

The social mind is tailored to the problem of predicting the mental states and actions of other
people. However, social cognition researchers have only scratched the surface of the …

Computational psychiatry is a rapidly growing field attempting to translate advances in
computational neuroscience and machine learning into improved outcomes for patients …

Regulating how fast to learn is critical for flexible behavior. Learning about the
consequences of actions should be slow in stable environments, but accelerate when that …

The cognitive model of depression has significantly influenced the understanding of
distorted cognitive processes in major depression; however, this model's conception of …

Controlling behavior to flexibly achieve desired goals depends on the ability to monitor one's
own performance. It is unknown how performance monitoring can be both flexible, to support …