The quantity and quality of research into autism and related conditions have increased
dramatically in recent years. Consequently we selectively review key accomplishments and …

Autism spectrum disorders (ASDs) are complex, heterogeneous disorders caused by an
interaction between genetic vulnerability and environmental factors. In an effort to better …

Background Autism is a complex neurodevelopmental disorder that usually presents in early
childhood and that is thought to be influenced by genetic and environmental factors …

Autism is a behaviorally defined neurodevelopmental disorder usually diagnosed in early
childhood that is characterized by impairment in reciprocal communication and speech …

Psychiatric disorders are debilitating diseases, affecting> 80 million people worldwide.
There are no causal cures for psychiatric disorders and available therapies only treat the …

There is great evidence in recent years that oxygen free radicals play an important role in
the pathophysiology of many neuropsychiatric disorders. The present study was performed …

In recent years, a substantial body of evidence has emerged demonstrating that purine and
pyrimidine synthesis and metabolism play major roles in controlling embryonic and fetal …

Slow, rhythmic oscillations (< 5 Hz) in the sleep electroencephalogram may be a sign of
synaptic plasticity occurring during sleep. The oscillations, referred to as slow-wave activity …

Methylation events play a critical role in the ability of growth factors to promote normal
development. Neurodevelopmental toxins, such as ethanol and heavy metals, interrupt …

Autism spectrum disorders are complex neuro-developmental disorders whose
neurobiology is proposed to be associated with oxidative stress which is induced by reactive …