In the brain, increases in neural activity drive changes in local blood flow via neurovascular
coupling. The common explanation for increased blood flow (known as functional …

Neuronal networks are capable of undergoing rapid structural and functional changes called
plasticity, which are essential for shaping circuit function during nervous system …

Temporal lobe epilepsy (TLE) is one of the most common types of epilepsy, yet
approximately one-third of patients are refractory to current anticonvulsive drugs, which …

Mesenchymal stromal cells (MSC) are widely recognized as potential effectors in
neuroprotective therapy. The protective properties of MSC were considered to be associated …

Transient receptor potential (TRP) channels are a widely expressed family of 28
evolutionarily conserved cationic ion channels that operate as primary detectors of chemical …

The glial cells astrocytes have long been recognized as important neuron-supporting
elements in brain development, homeostasis, and metabolism. After the discovery that the …

Astroglia are neural cells, heterogeneous in form and function, which act as supportive
elements of the central nervous system; astrocytes contribute to all aspects of neural …

Simple Summary Connexin hemichannels are formed by connexin protein family members,
and connect cytosol and extracellular milium. The function of connexin hemichannels cannot …

Transient receptor potential cation channels subfamily V member 4 (TRPV4) are non-
selective cation channels expressed in different cell types of the central nervous system …

During hypoxia, increases in cerebral blood flow maintain brain oxygen delivery. Here, we
describe a mechanism of brain oxygen sensing that mediates the dilation of …