[HTML][HTML] Drug–DNA interactions and their study by UV–Visible, fluorescence spectroscopies and cyclic voltametry

M Sirajuddin, S Ali, A Badshah - Journal of Photochemistry and …, 2013 - Elsevier
The present paper review the drug–DNA interactions, their types and applications of
experimental techniques used to study interactions between DNA and small ligand …

Metal compounds against neglected tropical diseases

YC Ong, S Roy, PC Andrews, G Gasser - Chemical reviews, 2018 - ACS Publications
Many first-line treatments for neglected tropical diseases identified by the World Health
Organization (WHO) are limited by one or more of the following: the development of drug …

Synthesis, crystal structure, Hirshfeld surface analysis, DNA binding, optical and nonlinear optical properties of Schiff bases derived from o-aminophenol

KS Munawar, S Ali, S Muhammad, M Ashfaq… - Journal of Molecular …, 2023 - Elsevier
The current work focuses on the synthesis of the two new Schiff base ligands derived from o-
aminophenol named 2-[(E)-(3-chlorophenyl) methylidene] amino-phenol (2AP3Cl) and 4 …

Pincer complexes derived from tridentate Schiff bases for their use as antimicrobial metallopharmaceuticals

A Aragón-Muriel, V Reyes-Márquez… - Inorganics, 2022 - mdpi.com
Within the current challenges in medicinal chemistry, the development of new and better
therapeutic agents effective against infectious diseases produced by bacteria, fungi, viruses …

Synthesis, characterization, biological screenings and interaction with calf thymus DNA as well as electrochemical studies of adducts formed by azomethine [2-((3, 5 …

M Sirajuddin, S Ali, A Haider, NA Shah, A Shah… - polyhedron, 2012 - Elsevier
Novel azomethine adducts of Sn (IV) have been synthesized by the reaction of RnSnCl4− n
(n= 1–3, R= CH3, n-C4H9, C6H5, C6H11) with 2-((3, 5-dimethylphenylimino) methyl) phenol …

Organotin (IV) complexes derived from tridentate Schiff base ligands: Synthesis, spectroscopic analysis, antimicrobial and antioxidant activity

S Saroya, S Asija, N Kumar, Y Deswal - Journal of the Indian Chemical …, 2022 - Elsevier
Organotin complexes of Schiff bases (derived from the condensation of hydrazides with
salicylaldehyde derivatives) were prepared and their characterization was done using …

Synthesis, spectroscopic characterization, X-ray crystal structure, antimicrobial, DNA-binding, alkaline phosphatase and insulin-mimetic studies of oxidovanadium (IV) …

KS Munawar, S Ali, MN Tahir, N Khalid… - Journal of …, 2020 - Taylor & Francis
A series of novel azomethine precursors were synthesized by the condensation reactions of
3-(trifluoromethyl) benzenamine (tfmb) with 2-hydroxybenzaldehyde (HL1)(tfmbs), 2, 3 …

Development of new tridentate ligands bearing hydrazone motif and their diorganotin (IV) complexes: synthesis, spectral, antimicrobial and molecular docking studies

N Kumar, S Asija, Y Deswal, S Saroya… - Research on Chemical …, 2022 - Springer
Current antimicrobial drug discovery and advancement attempts are aimed to identify new
complexes that can work effectively against the infections caused by microbes. The aim of …

Molecular spectroscopic and thermodynamic studies on the interaction of anti-platelet drug ticlopidine with calf thymus DNA

S Afrin, Y Rahman, T Sarwar, MA Husain, A Ali… - … Acta Part A: Molecular …, 2017 - Elsevier
Ticlopidine is an anti-platelet drug which belongs to the thienopyridine structural family and
exerts its effect by functioning as an ADP receptor inhibitor. Ticlopidine inhibits the …

Synthesis, characterization, biological screenings and interaction with calf thymus DNA of a novel azomethine 3-((3, 5-dimethylphenylimino) methyl) benzene-1, 2-diol

M Sirajuddin, S Ali, NA Shah, MR Khan… - Spectrochimica Acta Part …, 2012 - Elsevier
The novel azomethine, 3-((3, 5-dimethylphenylimino) methyl) benzene-1, 2-diol (HL) was
synthesized and characterized by elemental analysis, FT-IR, 1H, 13C NMR spectroscopy …